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Document and Entity Information - USD ($)	12 Months Ended
Document and Entity Information - USD ($)	Dec. 31, 2016	Feb. 17, 2017	Jun. 30, 2016
Document and Entity Information [Abstract]
Entity Registrant Name	Emergent BioSolutions Inc.
Entity Central Index Key	0001367644
Current Fiscal Year End Date	--12-31
Entity Well-known Seasoned Issuer	Yes
Entity Voluntary Filers	No
Entity Current Reporting Status	Yes
Entity Filer Category	Large Accelerated Filer
Entity Public Float			$ 920,000,000
Entity Common Stock, Shares Outstanding		40,687,639
Document Fiscal Year Focus	2016
Document Fiscal Period Focus	FY
Document Type	10-K
Amendment Flag	false
Document Period End Date	Dec. 31, 2016

Consolidated Balance Sheets - USD ($) $ in Thousands	Dec. 31, 2016	Dec. 31, 2015
Current assets:
Cash and cash equivalents	$ 271,513	$ 308,304
Accounts receivable, net	138,478	113,906
Inventories	74,002	60,887
Income tax receivable, net	9,996	6,573
Prepaid expenses and other current assets	16,229	18,458
Current assets of discontinued operations	0	29,282
Total current assets	510,218	537,410
Property, plant and equipment, net	376,448	327,808
In-process research and development	0	701
Intangible assets, net	33,865	40,758
Goodwill, net book value	41,001	41,001
Deferred tax assets, net	6,096	11,286
Other assets	2,483	2,155
Non-current assets of discontinued operations	0	76,365
Total assets	970,111	1,037,484
Current liabilities:
Accounts payable	34,649	37,970
Accrued expenses and other current liabilities	6,368	6,207
Accrued compensation	34,537	31,998
Notes payable, current portion	20,000	0
Contingent purchase consideration, current portion	3,266	2,109
Short-term deferred revenue	7,036	3,979
Current liabilities of discontinued operations	0	17,348
Total current liabilities	105,856	99,611
Contingent purchase consideration, net of current portion	9,919	23,046
Long-term indebtedness, net of current portion	248,094	246,892
Deferred revenue, net of current portion	8,433	3,426
Other liabilities	1,604	1,258
Non-current liabilities of discontinued operations	0	3,234
Total liabilities	373,906	377,467
Commitments and contingencies
Stockholders' equity:
Preferred stock, $0.001 par value; 15,000,000 shares authorized, 0 shares issued and outstanding at both December 31, 2016 and December 31, 2015	0	0
Common stock, $0.001 par value; 200,000,000 shares authorized, 40,996,890 shares issued and 40,574,060 shares outstanding at December 31, 2016; 100,000,000 shares authorized, 39,829,408 shares issued and 39,406,578 shares outstanding at December 31, 2015	41	40
Treasury stock, at cost, 422,830 common shares at both December 31, 2016 and December 31, 2015	(6,420)	(6,420)
Additional paid-in capital	352,435	317,971
Accumulated other comprehensive loss	(4,331)	(2,713)
Retained earnings	254,480	351,139
Total stockholders' equity	596,205	660,017
Total liabilities and stockholders' equity	$ 970,111	$ 1,037,484

Consolidated Balance Sheets (Parenthetical) - $ / shares	Dec. 31, 2016	Dec. 31, 2015
Stockholders' equity:
Preferred stock, par value (in dollars per share)	$ 0.001	$ 0.001
Preferred stock, shares authorized (in shares)	15,000,000	15,000,000
Preferred stock, shares issued (in shares)	0	0
Preferred stock, shares outstanding (in shares)	0	0
Common stock, par value (in dollars per share)	$ 0.001	$ 0.001
Common stock, shares authorized (in shares)	200,000,000	100,000,000
Common stock, shares issued (in shares)	40,996,890	39,829,408
Common stock, shares outstanding (in shares)	40,574,060	39,406,578
Treasury stock (in shares)	422,830	422,830

Consolidated Statements of Operations - USD ($) $ in Thousands	12 Months Ended
	Dec. 31, 2016	Dec. 31, 2015	Dec. 31, 2014
Revenues:
Product sales	$ 296,278	$ 328,969	$ 281,845
Contract manufacturing	49,138	42,968	30,944
Contracts and grants	143,366	117,394	91,677
Total revenues	488,782	489,331	404,466
Operating expenses:
Cost of product sales and contract manufacturing	131,284	107,486	101,963
Research and development	108,290	119,186	104,721
Selling, general and administrative	143,686	121,145	108,594
Income from operations	105,522	141,514	89,188
Other income (expense):
Interest income	1,053	572	320
Interest expense	(7,617)	(6,523)	(8,240)
Other income (expense), net	263	153	2,926
Total other income (expense)	(6,301)	(5,798)	(4,994)
Income from continuing operations before provision for income taxes	99,221	135,716	84,194
Provision for income taxes	36,697	44,300	29,928
Net Income from continuing operations	62,524	91,416	54,266
Loss from discontinued operations (net of tax)	(10,748)	(28,546)	(17,525)
Net income	$ 51,776	$ 62,870	$ 36,741
Net income per share - basic:
Net income from continuing operations-basic	$ 1.56	$ 2.37	$ 1.45
Net loss from discontinued operations-basic	(0.27)	(0.74)	(0.47)
Net income per share - basic (in dollars per share)	1.29	1.63	0.98
Net income per share - diluted:
Net income per share from continuing operations-diluted	1.35	2.02	1.26
Net loss per share from discontinued operations-diluted	(0.22)	(0.61)	(0.38)
Net income per share-diluted	$ 1.13	$ 1.41	$ 0.88
Weighted-average number of shares - basic (in shares)	40,184,159	38,595,435	37,344,891
Weighted-average number of shares - diluted (in shares)	49,335,112	47,255,842	45,802,807

Consolidated Statements of Comprehensive Income - USD ($) $ in Thousands	12 Months Ended
	Dec. 31, 2016	Dec. 31, 2015	Dec. 31, 2014
Consolidated Statements of Comprehensive Income [Abstract]
Net income	$ 51,776	$ 62,870	$ 36,741
Reclassification of cumulative currency translation adjustment to income, net of tax
Foreign currency translations, net of tax	(1,618)	295	457
Comprehensive income	$ 50,158	$ 63,165	$ 37,198

Consolidated Statements of Cash Flows - USD ($) $ in Thousands	12 Months Ended
	Dec. 31, 2016	Dec. 31, 2015	Dec. 31, 2014
Cash flows from operating activities:
Net income (loss)	$ 51,776	$ 62,870	$ 36,741
Adjustments to reconcile to net cash provided by operating activities:
Stock-based compensation expense	18,477	15,848	12,829
Other Depreciation and Amortization	38,229	35,335	32,453
Deferred income taxes	5,190	3,464	16,493
Change in fair value of contingent obligations	(10,838)	(10,599)	3,133
Write off of debt issuance costs	0	0	1,831
Impairment of in-process research and development	701	9,827	0
Impairment and abandonment of long-lived assets	5,569	1,147	0
Bad debt expense	0	3,481	0
Excess tax benefits from stock-based compensation	(10,619)	(11,281)	(5,987)
Other	452	271	1,284
Changes in operating assets and liabilities:
Accounts receivable	(22,446)	(64,351)	21,405
Inventories	(9,026)	(11,262)	4,229
Income taxes	(4,560)	(3,550)	(4,711)
Prepaid expenses and other assets	(2,089)	2,319	(8,472)
Accounts payable	(14,791)	4,749	(9,279)
Accrued expenses and other liabilities	624	45	2,685
Accrued compensation	2,236	2,680	4,539
Provision for chargebacks	0	(8)	299
Deferred revenue	4,602	3,474	2,846
Net cash provided by operating activities	53,487	44,459	112,318
Cash flows from investing activities:
Purchases of property, plant and equipment	(76,257)	(44,812)	(30,673)
Acquisitions, net of acquired cash	0	(650)	(179,379)
Net cash used in investing activities	(76,257)	(45,462)	(210,052)
Cash flows from financing activities:
Proceeds from convertible debenture, net of bank fees	0	0	241,588
Proceeds from borrowings on long-term indebtedness	0	2,000	1,000
Issuance of common stock subject to employee equity plans	17,125	25,961	14,078
Excess tax benefits from stock-based compensation	10,619	11,281	5,987
Principal payments on long-term indebtedness and line of credit	0	0	(62,000)
Distribution to Aptevo	(45,000)	0	0
Contingent obligation payments	(1,385)	(5,693)	(1,579)
Purchase of treasury stock	0	(100)	(200)
Net cash (used in) provided by financing activities	(18,641)	33,449	198,874
Effect of exchange rate changes on cash and cash equivalents	129	(150)	21
Net (decrease) increase in cash and cash equivalents	(41,282)	32,296	101,161
Cash and cash equivalents at beginning of year	312,795	280,499	179,338
Cash and cash equivalents at end of year	271,513	312,795	280,499
Supplemental disclosure of cash flow information:
Cash paid during the year for interest	8,210	7,751	3,761
Cash paid during the year for income taxes	10,081	28,271	4,711
Supplemental information on non-cash investing and financing activities:
Purchases of property, plant and equipment unpaid at year end	$ 13,459	$ 4,379	$ 5,394

Consolidated Statement of Changes in Stockholders' Equity - USD ($) $ in Thousands	$0.001 Par Value Common Stock [Member]	Additional Paid-in Capital [Member]	Treasury Stock [Member]	Accumulated Other Comprehensive Loss [Member]	Noncontrolling Interest in Subsidiary [Member]	Retained Earnings [Member]	Total
Balance at Dec. 31, 2013	$ 37	$ 247,637	$ (6,119)	$ (3,465)	$ (453)	$ 251,528	$ 489,165
Balance (in shares) at Dec. 31, 2013	37,036,996		(412,953)
Increase (Decrease) in Stockholders' Equity [Roll Forward]
Employee equity award plans activity	$ 1	26,585		0	0	0	26,586
Employee equity award plans activity (in shares)	1,092,876
Non-cash development expenses from joint venture					453	0	453
Treasury stock			$ (201)	0	0		(201)
Treasury stock (in shares)			(7,236)
Net income					0	36,741	36,741
Foreign currency translations, net of tax				457	0	0	457
Balance at Dec. 31, 2014	$ 38	274,222	$ (6,320)	(3,008)	0	288,269	553,201
Balance (in shares) at Dec. 31, 2014	38,129,872		(420,189)
Increase (Decrease) in Stockholders' Equity [Roll Forward]
Employee equity award plans activity	$ 2	43,749		0	0	0	43,751
Employee equity award plans activity (in shares)	1,699,536
Treasury stock			$ (100)	0	0		(100)
Treasury stock (in shares)			(2,641)
Net income				0	0	62,870	62,870
Foreign currency translations, net of tax				295	0	0	295
Balance at Dec. 31, 2015	$ 40	317,971	$ (6,420)	(2,713)	0	351,139	$ 660,017
Balance (in shares) at Dec. 31, 2015	39,829,408		(422,830)				39,406,578
Increase (Decrease) in Stockholders' Equity [Roll Forward]
Employee equity award plans activity	$ 1	34,464		0	0	0	$ 34,465
Employee equity award plans activity (in shares)	1,167,482
Separation of Aptevo						(148,435)	(148,435)
Treasury stock			$ 0	0	0		0
Treasury stock (in shares)			0
Net income				0	0	51,776	51,776
Foreign currency translations, net of tax				(1,618)	0	0	(1,618)
Balance at Dec. 31, 2016	$ 41	$ 352,435	$ (6,420)	$ (4,331)	$ 0	$ 254,480	$ 596,205
Balance (in shares) at Dec. 31, 2016	40,996,890		(422,830)				40,574,060

Nature of the business and organization

12 Months Ended

Dec. 31, 2016

Nature of the business and organization [Abstract]

Nature of the business and organization

1. Nature of the business and organization

Organization and business

Emergent BioSolutions Inc. (the "Company" or "Emergent") is a global life sciences company seeking to protect and enhance life by focusing on providing specialty products for civilian and military populations that address accidental, intentional and naturally emerging public health threats. The Company is focused on developing, manufacturing and commercializing medical countermeasures, or MCM, that address public health threats, or PHTs. The PHTs that the Company is addressing fall into two categories: Chemical, Biological, Radiological and Nuclear, or CBRN, as well as explosive-related threats; and emerging infectious diseases, or EID.

We have a portfolio of six revenue-generating products, as well as a pipeline of various investigational stage product candidates addressing select aspects of CBRN and EID threats. The U.S. government is the primary purchaser of our products and provides us with substantial funding for the development of many of our product candidates. A unique attribute of our investigational stage product portfolio is that many of our candidates are under an active development contract with significant funding from the U.S. government.

Our marketed products are:

BioThrax^® (Anthrax Vaccine Adsorbed), the only vaccine licensed by the U.S. Food and Drug Administration, or the FDA, for the general use prophylaxis and post-exposure prophylaxis of anthrax disease in combination with appropriate anti-bacterial drugs. BioThrax is also licensed in Singapore and by the Paul-Ehrlich-Institut of the German Federal Ministry of Health for general use prophylaxis of anthrax disease;

Anthrasil^® [Anthrax Immune Globulin Intravenous (Human)], the only polyclonal antibody therapeutic licensed by the FDA for the treatment of inhalational anthrax;

BAT^® [Botulism Antitoxin Heptavalent (A,B,C,D,E,F,G)- (Equine)], the only heptavalent therapeutic licensed by the FDA and Health Canada for the treatment of botulinum disease;

VIGIV [Vaccinia Immune Globulin Intravenous (Human)], the only therapeutic licensed by the FDA to address certain complications from smallpox vaccination;

RSDL^® (Reactive Skin Decontamination Lotion Kit), the only device cleared by the FDA to remove or neutralize chemical warfare agents and T-2 toxins from the skin; and

Trobigard™ (atropine sulfate, obidoxime chloride), an auto-injector device designed for intramuscular self-injection of atropine sulfate and obidoxime chloride, a nerve agent countermeasure. This product has not been approved by the FDA or any other regulatory agency, is not promoted or distributed in the U.S., and is only sold to non-U.S. authorized government buyers.

We also provide contract manufacturing services to third-party customers. We perform pharmaceutical product development and filling services for injectable and other sterile products, as well as process design, technical transfer, manufacturing validation, laboratory support, aseptic filling, lyophilization, final packaging and accelerated and ongoing stability studies.

Aptevo spin-off

On August 6, 2015, the Company announced its plan to separate into two independent publicly-traded companies. On August 1, 2016, the Company accomplished this plan through the completion of the spin-off of Aptevo Therapeutics Inc. ("Aptevo"), a biotechnology company focused on novel oncology and hematology therapeutics to meaningfully improve patients' lives.

Summary of significant accounting policies

12 Months Ended

Dec. 31, 2016

Summary of significant accounting policies [Abstract]

Summary of significant accounting policies

2. Summary of significant accounting policies

Basis of presentation and consolidation

The accompanying consolidated financial statements include the accounts of Emergent and its wholly owned and majority owned subsidiaries. All significant intercompany accounts and transactions have been eliminated in consolidation.

In anticipation of the spin-off, the Company realigned certain components of its biosciences business to the new Aptevo segment to be consistent with how the Company's chief operating decision maker ("CODM") allocates resources and makes decisions about the operations of the Company. Effective January 1, 2016, the Company changed its segment presentation to reflect this new structure, and recast all prior periods presented to conform to the new presentation. On August 1, 2016, the Company completed the spin-off of Aptevo. As of December 31, 2016, the results of operations and financial position of Aptevo are reflected as discontinued operations for all periods presented through the date of the spin-off. The historical financial statements and footnotes have been revised accordingly. See Note 3. "Discontinued operations" for further details regarding the spin-off. For periods following the spin-off, the Company reports financial results under one business segment.

Use of estimates

The preparation of financial statements in conformity with accounting principles generally accepted in the United States requires management to make estimates and assumptions that affect the reported amounts of assets and liabilities and the disclosure of contingent assets and liabilities at the date of the financial statements and the reported amounts of revenues and expenses during the reporting period. Actual results could differ from those estimates.

Cash and cash equivalents

Cash equivalents are highly liquid investments with a maturity of 90 days or less at the date of purchase and consist of time deposits and investments in money market funds with commercial banks and financial institutions. Also, the Company maintains cash balances with financial institutions in excess of insured limits. The Company does not anticipate any losses with such cash balances.

Fair value of measurements

The Company measures and records cash equivalents and investment securities considered available-for-sale at fair value in the accompanying financial statements. Fair value is defined as the exchange price that would be received for an asset or paid to transfer a liability, an exit price, in the principal or most advantageous market for the asset or liability in an orderly transaction between market participants on the measurement date. Valuation techniques used to measure fair value must maximize the use of observable inputs and minimize the use of unobservable inputs. The three-tier fair value hierarchy, which prioritizes the inputs used in measuring fair value include:

Level 1 —

Observable inputs for identical assets or liabilities such as quoted prices in active markets;

Level 2 —

Inputs other than quoted prices in active markets that are either directly or indirectly observable; and

Level 3 —

Unobservable inputs in which little or no market data exists, which are therefore developed by the Company using estimates and assumptions that reflect those that a market participant would use.

The carrying amounts of the Company's short-term financial instruments, which include cash and cash equivalents, accounts receivable and accounts payable, approximate their fair values due to their short maturities.

Significant customers and accounts receivable

The Company has derived a majority of its revenue from sales of BioThrax under contracts with the U.S. government. The Company's current Centers for Disease Control ("CDC"), an operating division of the U.S. Department of Health and Human Services ("HHS"), contract does not necessarily increase the likelihood that it will secure future comparable contracts with the U.S. government. The Company expects that a significant portion of the business that it will seek in the near future, in particular for BioThrax, will be under government contracts that present a number of risks that are not typically present in the commercial contracting process. U.S. government contracts for BioThrax are subject to unilateral termination or modification by the government. The Company may fail to achieve significant sales of BioThrax to customers in addition to the U.S. government, which would harm its growth opportunities. The Company may not be able to sustain or increase profitability. The Company may not be able to manufacture BioThrax consistently in accordance with FDA specifications.

For the years ended December 31, 2016, 2015 and 2014, the Company's primary customer was the HHS. For the years ended December 31, 2016, 2015 and 2014, revenues from HHS and HHS agencies comprised 83%, 86% and 83%, respectively, of total revenues. As of December 31, 2016 and 2015, the Company's accounts receivable balances were comprised of 83% and 83%, respectively, from this customer. The overall increase in the percentage of accounts receivable attributed to HHS was due primarily to the timing of payments received for BioThrax product sales under the Company's contract with the CDC. As of December 31, 2016 and 2015, unbilled accounts receivable, which is included in accounts receivable, were $48.0 million and $18.2 million, respectively. Unbilled accounts receivable relates to various service contracts for which work has been performed, though invoicing has not yet occurred. Accounts receivable are stated at invoice amounts and consist primarily of amounts due from the U.S. government, as well as amounts due under reimbursement contracts with other government entities and non-government organizations. If necessary, the Company records a provision for doubtful receivables to allow for any amounts which may be unrecoverable. This provision is based upon an analysis of the Company's prior collection experience, customer creditworthiness and current economic trends.

Concentrations of credit risk and uncertainties

Financial instruments that potentially subject the Company to concentrations of credit risk consist primarily of cash and cash equivalents and accounts receivable. The Company places its cash and cash equivalents with high quality financial institutions. Management believes that the financial risks associated with its cash and cash equivalents are minimal. Because accounts receivable consist primarily of amounts due from the U.S. government for product sales and from government agencies under government grants and development contracts, management deems there to be minimal credit risk.

Inventories

Inventories are stated at the lower of cost or net realizable value with cost being determined using a standard cost method, which approximates average cost. Average cost consists primarily of material, labor and manufacturing overhead expenses (including fixed production-overhead costs) and includes the services and products of third party suppliers. The Company analyzes its inventory levels quarterly and writes down, in the applicable period, inventory that has become obsolete, inventory that has a cost basis in excess of its expected net realizable value and inventory in excess of expected customer demand. The Company also writes off, in the applicable period, the costs related to expired inventory. Costs of purchased inventories are recorded using weighted-average costing. The Company determines normal capacity for each production facility and allocates fixed production-overhead costs on that basis.

Property, plant and equipment

Property, plant and equipment are stated at cost. Depreciation is computed using the straight-line method over the following estimated useful lives:

Buildings	31-39 years
Building improvements	10-39 years
Furniture and equipment	3-15 years
Software	3-7 years or product life
Leasehold improvements	Lesser of the asset life or lease term

Upon retirement or sale, the cost of assets disposed of and the related accumulated depreciation are removed from the accounts and any resulting gain or loss is credited or charged to operations. Repairs and maintenance costs are expensed as incurred.

The Company capitalizes internal-use software when both (a) the software is internally developed, acquired, or modified solely to meet the entity's internal needs and (b) during the software's development or modification, no substantive plan either exists or is being developed to market the software externally. Capitalization of qualifying internal-use software costs begins when the preliminary project stage is completed, management with the relevant authority, implicitly or explicitly, authorizes and commits to the funding of the software project, and it is probable that the project will be completed and the software will be used to perform the function intended.

Income taxes

Income taxes are accounted for using the liability method. Deferred tax assets and liabilities are recognized for future tax consequences attributable to differences between financial statement carrying amounts of existing assets and liabilities and their respective tax bases and net operating loss and research and development tax credit carryforwards. Deferred tax assets and liabilities are measured using enacted tax rates expected to apply to taxable income in the year in which those temporary differences are expected to be recovered or settled.

The Company's ability to realize deferred tax assets depends upon future taxable income as well as the limitations discussed below. For financial reporting purposes, a deferred tax asset must be reduced by a valuation allowance if it is more likely than not that some portion or all of the deferred tax assets will not be realized prior to expiration. The Company considers future taxable income and ongoing tax planning strategies in assessing the need for valuation allowances. In general, if the Company determines that it is more likely than not to realize more than the recorded amounts of net deferred tax assets in the future, the Company will reverse all or a portion of the valuation allowance established against its deferred tax assets, resulting in a decrease to the provision for income taxes in the period in which the determination is made. Likewise, if the Company determines that it is not more likely than not to realize all or part of the net deferred tax asset in the future, the Company will establish a valuation allowance against deferred tax assets, with an offsetting increase to the provision for income taxes, in the period in which the determination is made.

Under sections 382 and 383 of the Internal Revenue Code, if an ownership change occurs with respect to a "loss corporation", as defined, there are annual limitations on the amount of net operating losses and deductions that are available. The Company believes the use of net operating losses and research and development tax credits acquired in the Trubion acquisition will not be significantly limited. Due to the acquisition of Microscience in 2005 and the Company's initial public offering, the Company believes the use of the operating losses incurred prior to 2005 will be significantly limited.

Because tax laws are complex and subject to different interpretations, significant judgment is required. As a result, the Company makes certain estimates and assumptions, in (1) calculating the Company's income tax expense, deferred tax assets and deferred tax liabilities, (2) determining any valuation allowance recorded against deferred tax assets and (3) evaluating the amount of unrecognized tax benefits, as well as the interest and penalties related to such uncertain tax positions. The Company's estimates and assumptions may differ significantly from tax benefits ultimately realized.

Revenue recognition

The Company recognizes revenues from product sales and contract manufacturing if four basic criteria have been met:



there is persuasive evidence of an arrangement;



delivery has occurred or title has passed to the Company's customer;



the fee is fixed or determinable; and



collectability is reasonably assured.

Under the Company's contracts with the CDC, the Company invoices the CDC and recognizes the related revenue upon acceptance by the government at delivery site, at which time title to the product passes to the CDC.

Agreements with multiple components ("deliverables" or "items") are evaluated to determine if the deliverables can be divided into more than one unit of accounting. An item can generally be considered a separate unit of accounting if both of the following criteria are met:

(1) the delivered item or items have value to the customer on a standalone basis. The item or items have value on a standalone basis if they are sold separately by any vendor or the customer could resell the delivered item(s) on a standalone basis. In the context of a customer's ability to resell the delivered item(s), this criterion does not require the existence of an observable market for the deliverable(s); and

(2) if the arrangement includes a general right of return relative to the delivered item(s), delivery or performance of the undelivered item(s) is considered probable and substantially in control of the Company. Items that cannot be divided into separate units are combined with other units of accounting, as appropriate. Consideration received is allocated among the separate units based on the relative selling price of each deliverable. The Company deems service to have been rendered if no continuing obligation exists on the part of the Company.

The Company's contract with the Biomedical Advanced Research and Development Authority ("BARDA") to establish a Center for Innovation in Advanced Development and Manufacturing ("CIADM") is a service arrangement that includes multiple elements. The CIADM contract requires the Company to provide a flexible infrastructure to supply medical countermeasures to the U.S. government over the contract period and includes such items as construction and facility design, workforce development and licensure of a pandemic flu vaccine. Since none of the individual elements by themselves satisfy the purpose of the contract, the Company has concluded that the CIADM contract elements cannot be separated as they do not have stand-alone value to the U.S. government. Therefore, the Company has concluded that there is a single unit of accounting associated with the CIADM contract. The Company recognizes revenue under the CIADM contract on a straight-line basis, based upon its estimate of the total payments to be received under the contract. The Company analyzes the estimated payments to be received on a quarterly basis to determine if an adjustment to revenue is required. Changes in estimates attributed to modifications in the estimate of total payments to be received are recorded prospectively.

The Company's BAT contract with BARDA is a service arrangement that includes multiple elements. The deliverables to BARDA include the supply product to the SNS, perform stability testing for the product, achievement of extended product expiry dating, maintenance of horse populations and plasma extraction. The Company has determined that each of the deliverables above represents a separate units of accounting as they have standalone value to the U.S. government. The Company allocated the value of the contract to the undelivered elements based on best estimate of selling price ("BESP"). BESP methodology for the deliverables, excluding the product sales, was developed using a cost build-up for internal and external costs, plus a specified mark-up. The allocation of value to the product sales was based on the remaining unallocated value. The Company intends to complete the final delivery of the BAT product in 2017. The Company recognizes revenue for:

BAT product sales upon delivery to the SNS;

stability testing based on the required testing schedule of the product;

extended product expiry based on achievement of the extension;

horse maintenance based on a per horse basis; and

plasma collection on a per liter basis.

The Company's contracts for VIGIV with the CDC and for Anthrasil with BARDA are service arrangements that include multiple elements. The deliverables to BARDA include to supply product to the SNS, perform stability testing for the product, achievement of extended product expiry dating and plasma extraction. The Company has determined that each of the deliverables above represents separate units of accounting as they have standalone value to the U.S. government. The Company allocated the value of the contract to the undelivered elements based on best estimate of selling price ("BESP"). BESP methodology for the deliverables, excluding the product sales, was developed using a cost build-up for internal and external costs, plus a specified mark-up. The allocation of value to the product sales was based on the remaining unallocated value. The Company recognizes revenue for:

VIGIV and Anthrasil product sales upon delivery to the CDC;

stability testing based on the required testing schedule of the product;

extended product expiry based on achievement of the extension; and

plasma collection on a per liter basis.

The Company's contract for the NuThrax product candidate with BARDA, which was entered into on September 30, 2016 is a service arrangement that includes multiple elements. The deliverables to BARDA are the completion of development for NuThrax and the procurement of product for the SNS. The Company has determined that each of the deliverables above are a separate unit of accounting as they have standalone value to the U.S. government. The Company allocated the value of the contract to the undelivered elements based on best estimate of selling price ("BESP"). BESP methodology for the development deliverable was developed using a cost build-up for internal and external costs, plus a specified mark-up. The allocation of value to the product sales was based on the remaining unallocated value.

Revenue associated with non-refundable upfront license fees under arrangements where the license fees and research and development activities cannot be accounted for as separate units of accounting is deferred and recognized as revenue either on a straight-line basis over the Company's continued involvement in the research and development process or based on the proportional performance of the Company's expected future obligation under the contract. Revenues from the achievement of research and development milestones, if deemed substantive, are recognized as revenue when the milestones are achieved, and the milestone payments are due and collectible. If not deemed substantive, the Company recognizes such milestone as revenue on a straight-line basis over the remaining expected term of continued involvement in the research and development process.

Milestones are considered substantive if all of the following conditions are met: (1) the milestone is non-refundable, (2) achievement of the milestone was not reasonably assured at the inception of the arrangement, (3) substantive effort is involved to achieve the milestone, and (4) the amount of the milestone appears reasonable in relation to the effort expended. Payments received in advance of work performed are recorded as deferred revenue.

The Company generates contracts and grants revenue from cost-plus-fee contracts. Revenues from reimbursable contracts are recognized as costs are incurred, generally based on allowable costs incurred during the period, plus any recognizable earned fee. The Company considers fixed fees under cost-plus-fee contracts to be earned in proportion to the allowable costs incurred in performance of the contract. The Company analyzes costs for contracts and reimbursable grants to ensure reporting of revenues gross versus net is appropriate. For each of the three years in the period ended December 31, 2016, the costs incurred under the contracts and grants approximated the revenue earned.

Research and development

We expense research and development costs as incurred. Our research and development expenses consist primarily of:

personnel-related expenses;

fees to professional service providers for, among other things, analytical testing, independent monitoring or other administration of our clinical trials and obtaining and evaluating data from our clinical trials and non-clinical studies;

costs of contract manufacturing services for clinical trial material; and

costs of materials used in clinical trials and research and development.

We intend to focus on developing innovative products based on our platforms with a focus on third-party funding. We plan to seek funding for development activities from external sources and third parties, such as governments and non-governmental organizations, or through collaborative partnerships. We expect our research and development spending will be dependent upon such factors as the results from our clinical trials, the availability of reimbursement of research and development spending, the number of product candidates under development, the size, structure and duration of any clinical programs that we may initiate, the costs associated with manufacturing our product candidates on a large-scale basis for later stage clinical trials, and our ability to use or rely on data generated by government agencies, such as studies involving BioThrax conducted by the CDC.

Mergers and Acquisitions

In a business combination, the acquisition method of accounting requires that the assets acquired and liabilities assumed be recorded as of the date of the merger or acquisition at their respective fair values with limited exceptions. Assets acquired and liabilities assumed in a business combination that arise from contingencies are recognized at fair value if fair value can reasonably be estimated. If the acquisition date fair value of an asset acquired or liability assumed that arises from a contingency cannot be determined, the asset or liability is recognized if probable and reasonably estimable; if these criteria are not met, no asset or liability is recognized. Fair value is defined as the exchange price that would be received for an asset or paid to transfer a liability (an exit price) in the principal or most advantageous market for the asset or liability in an orderly transaction between market participants on the measurement date. Accordingly, the Company may be required to value assets at fair value measures that do not reflect the Company's intended use of those assets. Any excess of the purchase price (consideration transferred) over the estimated fair values of net assets acquired is recorded as goodwill. Transaction costs and costs to restructure the acquired company are expensed as incurred. The operating results of the acquired business are reflected in the Company's consolidated financial statements after the date of the merger or acquisition. If the Company determines the assets acquired do not meet the definition of a business under the acquisition method of accounting, the transaction will be accounted for as an acquisition of assets rather than a business combination and, therefore, no goodwill will be recorded.

The fair values of intangible assets, including acquired in-process research and development ("IPR&D"), are determined utilizing information available at or near the merger or acquisition date based on expectations and assumptions that are deemed reasonable by management. Given the considerable judgment involved in determining fair values, the Company typically obtains assistance from third-party valuation specialists for significant items. Amounts allocated to acquired IPR&D are capitalized and accounted for as indefinite-lived intangible assets. Upon successful completion of each project, the Company will make a separate determination as to the remaining useful life of the asset and begin amortization. The judgments made in determining estimated fair values assigned to assets acquired and liabilities assumed in a business combination, as well as asset lives, can materially affect the Company's results of operations.

The fair values of identifiable intangible assets related to currently marketed products and product rights are primarily determined by using an "income approach" through which fair value is estimated based on each asset's discounted projected net cash flows. The Company's estimates of market participant net cash flows consider historical and projected pricing, margins and expense levels, the performance of competing products where applicable, relevant industry and therapeutic area growth drivers and factors, current and expected trends in technology and product life cycles, the time and investment that will be required to develop products and technologies, the ability to obtain marketing and regulatory approvals, the ability to manufacture and commercialize the products, the extent and timing of potential new product introductions by the Company's competitors, and the life of each asset's underlying patent, if any. The net cash flows are then probability-adjusted where appropriate to consider the uncertainties associated with the underlying assumptions, as well as the risk profile of the net cash flows utilized in the valuation. The probability-adjusted future net cash flows of each product are then discounted to present value utilizing an appropriate discount rate.

The fair values of identifiable intangible assets related to IPR&D are determined using an income approach, through which fair value is estimated based on each asset's probability-adjusted future net cash flows, which reflect the different stages of development of each product and the associated probability of successful completion. The net cash flows are then discounted to present value using an appropriate discount rate. Indefinite-lived intangible assets are tested for impairment annually or whenever events or changes in circumstances indicate that its carrying amount may not be recoverable.

In process research and development and long-lived assets

The Company assesses IPR&D assets for impairment on an annual basis or more frequently if indicators of impairment are present. The Company's annual assessment includes a comparison of the fair value of IPR&D assets to existing carrying value, and recognizes an impairment when the carrying value is greater than the determined fair value. The Company believes that the assumptions used in valuing the intangible and IPR&D assets are reasonable and are based upon its best estimate of likely outcomes of sales and clinical development. The underlying assumptions and estimates used to value these assets are subject to change in the future, and actual results may differ significantly from the assumptions and estimates. The Company has selected October 1 as its annual impairment test date for indefinite-lived intangible assets.

The Company assesses the recoverability of its long-lived assets or asset groups for which an indicator of impairment exists by determining whether the carrying value of such assets can be recovered through undiscounted future operating cash flows. If the Company concludes that the carrying value will not be recovered, the Company measures the amount of such impairment by comparing the fair value to the carrying value of the assets or asset groups.

Goodwill

The Company assesses the carrying value of goodwill on an annual basis, or whenever events or changes in circumstances indicate the carrying value of goodwill may not be recoverable, to determine whether any impairment in this asset may exist and, if so, the extent of such impairment. The provisions of the relevant accounting guidance require that the Company perform a two-step impairment test. In the first step, the Company compares the fair value of its reporting unit to the carrying value of the reporting unit. If the carrying value of the reporting unit exceeds the fair value of the reporting unit, then the second step of the impairment test is performed in order to determine the implied fair value of the reporting unit's goodwill. If the carrying value of the reporting unit's goodwill exceeds its implied fair value, an impairment loss equal to the difference is recognized. The Company calculates the fair value of the reporting unit utilizing the income approach. The income approach utilizes a discounted cash flow model, using a discount rate based on the Company's estimated weighted average cost of capital. The Company also evaluates goodwill for all reporting units using the qualitative assessment method, which permits companies to qualitatively assess whether it is more-likely-than-not that the fair value of a reporting unit is less than its carrying amount. The Company considers developments in its operations, the industry in which it operates and overall macroeconomic factors that could have affected the fair value of the reporting unit since the date of the most recent quantitative analysis of a reporting unit's fair value.

The determination of the fair value of a reporting unit is judgmental in nature and involves the use of significant estimates and assumptions. The estimates and assumptions used in calculating fair value include identifying future cash flows, which requires that the Company makes a number of critical legal, economic, market and business assumptions that reflect best estimates as of the testing date. The Company's assumptions and estimates may differ significantly from actual results, or circumstances could change that would cause the Company to conclude that an impairment now exists or that it previously understated the extent of impairment. The Company selected October 1 as its annual impairment test date.

Contingent Consideration

The Company records contingent consideration associated with (a) sales based royalties and (b) development and regulatory milestones at fair value. The fair value model used to calculate this obligation is based on the income approach (a discounted cash flow model) that has been risk adjusted based on the probability of achievement of net sales and achievement of the milestones. The inputs the Company uses for determining the fair value of the contingent consideration associated with sales based royalties and development and regulatory milestones are Level 3 fair value measurements. The Company re-evaluates the fair value on a quarterly basis. Changes in the fair value can result from adjustments to the discount rates and updates in the assumed timing of or achievement of net sales. Any future increase in the fair value of the contingent consideration associated with sales based royalties along with development and regulatory milestones are based on an increased likelihood that the underlying net sales or milestones will be achieved.

The associated payment or payments which will become due and payable for sales based royalties associated with marketed products will result in a charge to cost of product sales and contract manufacturing in the period in which the increase is determined. Similarly, any future decrease in the fair value of contingent consideration associated with sales based royalties will result in a reduction in cost of product sales and contract manufacturing. The changes in fair value for potential future sales based royalties associated with product candidates in development will result in a charge to selling, general and administrative expense in the period in which the increase is determined. Similarly, any future decrease in the fair value of contingent consideration associated with potential future sales based royalties for products candidates will result in a reduction in selling, general and administrative expense.

The associated payment or payments which will become due and payable for development and regulatory milestones will result in a charge to research and development expense in the period in which the increase is determined. Similarly, any future decrease in the fair value for development and regulatory milestones will result in a reduction in research and development expense.

Earnings per share

The Company calculates basic earnings per share by dividing net income by the weighted average number of shares of common stock outstanding during the period.

For the years ended December 31, 2016, 2015 and 2014, the Company calculated diluted earnings per share using the if-converted method by dividing the adjusted net income by the adjusted weighted average number of shares of common stock outstanding during the period. The adjusted net income is adjusted for interest expense and amortization of debt issuance cost, both net of tax, associated with the Company's 2.875% Convertible Senior Notes due 2021 (the "Notes"). The weighted average number of diluted shares is adjusted for the potential dilutive effect of the exercise of stock options and the vesting of restricted stock units along with the assumption of the conversion of the Notes, each at the beginning of the period.

Accounting for stock-based compensation

The Company has two stock-based employee compensation plans, the Fourth Amended and Restated Emergent BioSolutions Inc. 2006 Stock Incentive Plan (the "2006 Plan") and the Emergent BioSolutions Employee Stock Option Plan (the "2004 Plan" and together with the 2006 Plan, the "Emergent Plans"). The Company has granted options to purchase shares of common stock under the Emergent Plans and has granted restricted stock units under the 2006 Plan. The Emergent Plans have both incentive and non-qualified stock option features. The Company no longer grants equity awards under the 2004 Plan.

As of December 31, 2016, an aggregate of 18.9 million shares of common stock were authorized for issuance under the 2006 Plan, of which a total of approximately 6.1 million shares of common stock remain available for future awards to be made to plan participants. The exercise price of each option must be not less than 100% of the fair market value of the shares underlying such option on the date of grant. Awards granted under the 2006 Plan have a contractual life of no more than 10 years. The terms and conditions of equity awards (such as price, vesting schedule, term and number of shares) under the Emergent Plans are determined by the compensation committee of the Company's board of directors, which administers the Emergent Plans. Each equity award granted under the Emergent Plans vests as specified in the relevant agreement with the award recipient and no option can be exercised after ten years from the date of grant.

The Company determines the fair value of restricted stock units using the closing market price of the Company's common stock on the day prior to the date of grant. The Company utilizes the Black-Scholes valuation model for estimating the fair value of all stock options granted. Set forth below are the assumptions used in valuing the stock options granted and a discussion of the Company's methodology for developing each of the assumptions used:

	Year Ended December 31,
		2016	2015	2014
Expected dividend yield		0%	0%	0%
Expected volatility		31-33%	34-35%	35-38%
Risk-free interest rate		0.93-1.22%	1.27-1.61%	1.14-1.65%
Expected average life of options		4.3 years	4.3 years	4.5 years



Expected dividend yield — the Company does not pay regular dividends on its common stock and does not anticipate paying any dividends in the foreseeable future.



Expected volatility — a measure of the amount by which a financial variable, such as share price, has fluctuated (historical volatility) or is expected to fluctuate (implied volatility) during a period. The Company analyzed its own historical volatility to estimate expected volatility over the same period as the expected average life of the options.



Risk-free interest rate — the range of U.S. Treasury rates with a term that most closely resembles the expected life of the option as of the date on which the option is granted.



Expected average life of options — the period of time that options granted are expected to remain outstanding, based primarily on the Company's expectation of optionee exercise behavior subsequent to vesting of options.

Comprehensive income

Comprehensive income is comprised of net income and other changes in equity that are excluded from net income. The Company includes translation gains and losses incurred when converting its subsidiaries' financial statements from their functional currency to the U.S. dollar in accumulated other comprehensive income.

Foreign currencies

Except for the Company's Canadian subsidiaries, the local currency is the functional currency for the Company's foreign subsidiaries and, as such, assets and liabilities are translated into U.S. dollars at year-end exchange rates. Income and expense items are translated at average exchange rates during the year. Translation adjustments resulting from this process are charged or credited to other comprehensive income. The Company's Canadian subsidiaries functional currency is U.S. dollars due primarily to a significant amount of the transactions of the subsidiaries being denominated in U.S. dollars.

Capitalized interest

The Company capitalizes interest based on the cost of major ongoing capital projects which have not yet been placed in service. For the years ended December 31, 2016, 2015 and 2014, the Company incurred interest of $8.3 million, $7.8 million and $7.5 million, respectively. Of these amounts, the Company capitalized $2.2 million, $2.9 million and $2.5 million, respectively.

Recently issued and adopted accounting standards

In April 2014, the Financial Accounting Standards Board ("FASB") issued Accounting Standards Update ("ASU") No. 2014-08, Presentation of Financial Statements (Topic 205) and Property, Plant, and Equipment (Topic 360): Reporting Discontinued Operations and Disclosures of Disposals of Components of an Entity ("ASU No. 2014-08"). ASU No. 2014-08 limits discontinued operations reporting to disposals of components of an entity that represent strategic shifts that have (or will have) a major effect on an entity's operations and financial results. ASU No. 2014-08 also requires expanded disclosures for discontinued operations and disposals of individually significant components of an entity that do not qualify for discontinued operations reporting. ASU No. 2014-08 was effective for disposals and components classified as held-for-sale that occurred within annual periods beginning on or after December 15, 2014, and interim periods within those years. Early adoption was permitted. The new guidance is effective for the Company prospectively for all disposals of components of an entity that occurred after January 1, 2015. The spin-off of Aptevo by the Company on August 1, 2016 meets the definition of a discontinued operation under the new guidance and, as a result, the Company reflected the provisions of the new guidance for the years ended December 31, 2016, 2015 and 2014.

In May 2014, the FASB issued ASU No. 2014-09, Summary and Amendments That Create Revenue from Contracts with Customers (Topic 606) and Other Assets and Deferred Costs—Contracts with Customers (Subtopic 340-40) ("ASU No. 2014-09"). ASU No. 2014-09 supersedes the revenue recognition requirements in Topic 605, Revenue Recognition, as well as most industry-specific guidance, and significantly enhances comparability of revenue recognition practices across entities and industries by providing a principles-based, comprehensive framework for addressing revenue recognition issues. In order for a provider of promised goods or services to recognize as revenue the consideration that it expects to receive in exchange for the promised goods or services, the provider should apply the following five steps: (1) identify the contract with a customer(s); (2) identify the performance obligations in the contract; (3) determine the transaction price; (4) allocate the transaction price to the performance obligations in the contract; and (5) recognize revenue when (or as) the entity satisfies a performance obligation. ASU No. 2014-09 also specifies the accounting for some costs to obtain or fulfill a contract with a customer and provides enhanced disclosure requirements. The standard will be effective for annual reporting periods beginning after December 15, 2017, including interim periods within that reporting period, which for the Company will be its 2018 first quarter. The Company is permitted to use either the retrospective or the modified retrospective method when adopting ASU No. 2014-09. The Company has begun an initial assessment of the potential impact that ASU No. 2014-09 will have on its financial statements and disclosures and believes that there could be changes to the revenue recognition related to the Company's multiple element contracts, primarily those with the U.S. government.

In August 2014, the FASB issued ASU No. 2014-15, Presentation of Financial Statements - Going Concern (Subtopic 205-40): Disclosure of Uncertainties about an Entity's Ability to Continue as a Going Concern ("ASU No. 2014-15"). The amendment requires management to evaluate, for each annual and interim reporting period, whether there are conditions and events, considered in the aggregate, that raise substantial doubt about an entity's ability to continue as a going concern within one year after the date the financial statements are issued or are available to be issued. If substantial doubt is raised, additional disclosures around management's plan to alleviate these doubts are required. This update was effective for all annual periods and interim reporting periods ending after December 15, 2016. As of December 31, 2016, the Company adopted this guidance and it did not have a material impact on the current disclosures in the financial statements.

In April 2015, the FASB issued ASU No. 2015-03, Interest - Imputation of Interest (Subtopic 835-30) ("ASU No. 2015-03"), which simplifies the presentation of debt issuance costs. ASU No. 2015-03 requires that debt issuance costs related to a recognized debt liability be presented in the balance sheet as a direct deduction from the carrying amount of that debt liability, consistent with debt discounts. Prior to the issuance of ASU 2015-03, debt issuance costs were required to be presented as an asset on the balance sheet. ASU No. 2015-03 is effective for interim and annual periods beginning after December 15, 2015. During 2016, the Company adopted and applied the guidance on the consolidated financial statements and related disclosures on a retrospective basis.

In March 2016, the FASB issued ASU No. 2016-09, Compensation - Stock Compensation (Topic 718) ("ASU No. 2016-09"). ASU No. 2016-09 simplifies several aspects of the accounting for share-based payment award transactions, including: (1) the income tax consequences, (2) classification of awards as either equity or liabilities, and (3) classification on the statement of cash flows. ASU No. 2016-09 is effective for the annual reporting period beginning after December 15, 2016, including interim periods within that reporting period, with early adoption permitted. The Company is currently evaluating the impact that the adoption of ASU No. 2016-09 will have on the consolidated financial statements and related disclosures.

There are no other recently issued accounting pronouncements that are expected to have a material effect on the Company's financial position, results of operations or cash flows.

Discontinued operations

12 Months Ended

Dec. 31, 2016

Discontinued operations [Abstract]

Discontinued operations

3. Discontinued operations

On August 1, 2016, the Company completed the spin-off of Aptevo through the distribution of 100% of the outstanding shares of common stock of Aptevo to the Company's shareholders (the "Distribution"). The Distribution was made to the Company's shareholders of record as of the close of business on July 22, 2016 (the "Record Date"), who received one share of Aptevo common stock for every two shares of Emergent common stock held as of the Record Date. The Distribution was intended to qualify as a tax-free distribution for federal income tax purposes in the United States. In the aggregate, approximately 20.2 million shares of Aptevo common stock were distributed to the Company's shareholders of record as of the Record Date in the Distribution. After the Distribution, the Company no longer holds shares of Aptevo's common stock. In addition, on August 1, 2016, the Company entered into a non-negotiable, unsecured promissory note with Aptevo to provide an additional $20 million in funding, which the Company paid in January 2017.

The historical balance sheet and statements of operations of Aptevo have been presented as discontinued operations in the consolidated financial statements and prior periods have been restated. Discontinued operations include results of Aptevo's business except for certain allocated corporate overhead costs and certain costs associated with transition services provided by the Company to Aptevo. These allocated costs remain part of continuing operations. Due to differences between the basis of presentation for discontinued operations and the basis of presentation as a stand-alone company, the financial results of Aptevo included within discontinued operations for the Company may not be indicative of actual financial results of Aptevo.

In conjunction with the spin-off, the Company entered into a Separation and Distribution Agreement with Aptevo to effect the separation of Aptevo from the Company (the "Separation"). The Company also entered into various other agreements to provide a framework for its relationship with Aptevo after the Separation, including a manufacturing services agreement, transition services agreement, a tax matters agreement and an employee matters agreement.

The Separation and Distribution Agreement with Aptevo sets forth, among other things, the assets that were transferred, the liabilities assumed, and the contracts that were assigned to each of Aptevo and the Company as part of the Separation of the Company into two companies, and provided for when and how these transfers, assumptions and assignments were to occur.

Under the terms of the manufacturing services agreement, the Company agreed to provide contract manufacturing services for certain of Aptevo's products commencing on the date of the Distribution. The contract has a term of ten years. As of December 31, 2016, approximately $0.8 million of contract manufacturing services revenue is associated with the provision of services to Aptevo.

Under the terms of the transition services agreement, the Company agreed to provide on an interim, transitional basis, various services, including, but not limited to, accounts payable administration, information technology services, regulatory and clinical support, general administrative services and other support services commencing on the date of the Distribution and terminating up to two years following the date of the Distribution. During the year ended December 31, 2016, approximately $1.1 million of transition services revenue has been recorded in contracts and grants.

The tax matters agreement governs the respective rights, responsibilities and obligations of Aptevo and the Company with respect to taxes (including taxes arising in the ordinary course of business and taxes, if any, incurred as a result of any failure of the Distribution and certain related transactions to qualify as tax-free for U.S. federal income tax purposes), tax attributes, tax returns, tax proceedings and certain other tax matters.

The employee matters agreement governs certain compensation and employee benefit obligations and allocates liabilities and responsibilities relating to employment matters, employee compensation and benefit plans and programs and other related matters, including the transfer or assignment of employees from the Company to Aptevo.

The following table represents the carrying value of Aptevo's assets and liabilities distributed as part of the Separation on August 1, 2016:

(in thousands)	August 1, 2016

Assets:
Cash and cash equivalents	$	45,000
Accounts receivable, net		4,465
Inventories		11,959
Note receivable		20,000
Other current assets		4,870
Current assets of discontinued operations		86,294

Property, plant and equipment, net		6,128
In-process research and development		41,800
Intangible assets, net		15,402
Goodwill		13,902
Non-current assets of discontinued operations		77,232
Total assets of discontinued operations	$	163,526

Liabilities:
Accounts payable	$	6,285
Accrued expenses and other current liabilities		64
Accrued compensation		2,456
Contingent consideration		191
Provisions for chargebacks		2,341
Deferred revenue, current portion		433
Current liabilities of discontinued operations		11,770

Deferred revenue, net of current portion		3,232
Other liabilities		91
Non-current liabilities of discontinued operations		3,323
Total liabilities of discontinued operations	$	15,093

The following table represents Aptevo's assets and liabilities presented as discontinued operations and classified as held-for-disposition as of December 31, 2015:

(in thousands)	December 31, 2015

Assets:
Cash and cash equivalents	$	4,492
Accounts receivable, net		6,861
Inventories		16,049
Prepaid expenses and other current assets		1,880
Current assets of discontinued operations		29,282

Property, plant and equipment, net		4,046
In-process research and development		41,800
Intangible assets, net		16,617
Goodwill		13,902
Non-current assets of discontinued operations		76,365
Total assets of discontinued operations	$	105,647

Liabilities:
Accounts payable	$	8,134
Accrued expenses and other current liabilities		22
Accrued compensation		2,684
Contingent consideration, current portion		306
Provisions for chargebacks		2,238
Deferred revenue, current portion		3,964
Current liabilities of discontinued operations		17,348

Deferred revenue, net of current portion		3,163
Other liabilities		71
Non-current liabilities of discontinued operations		3,234
Total liabilities of discontinued operations	$	20,582

The following table summarizes results from discontinued operations of Aptevo included in the consolidated statements of operations:

	Years ended December 31,
(in thousands)	2016			2015			2014

Revenues:
Product sales	$	21,183		$	27,947		$	30,036
Collaborations		187			5,511			15,636
Total revenues		21,370			33,458			45,672

Operating expense:
Cost of product sales		11,556			16,809			16,449
Research and development		18,024			34,811			46,108
Selling, general and administrative		23,792			27,313			14,248
Loss from operations		(32,002	)		(45,475	)		(31,133	)

Other income (expense), net:		(41	)		(472	)		-

Loss from discontinued operations before benefit from income taxes		(32,043	)		(45,947	)		(31,133	)
Benefit from income taxes		(21,295	)		(17,401	)		(13,608	)
Net loss from discontinued operations	$	(10,748	)	$	(28,546	)	$	(17,525	)

The following table summarizes the cash flows of Aptevo included in the years ended December 31, 2016, 2015 and 2014 consolidated statements of cash flows:

	Years ended December 31,
(in thousands)	2016			2015			2014
Net cash (used in) provided by operating activities	$	(10,299	)	$	(12,716	)	$	(14,683	)
Net cash used in investing activities		(1,926	)		(1,518	)		(48,822	)
Net cash provided by (used in) financing activities		7,733			15,012			67,219

Net increase (decrease) in cash and cash equivalents	$	(4,492	)	$	778		$	3,714

- Definition

The entire disclosure related to a disposal group. Includes, but is not limited to, a discontinued operation, disposal classified as held-for-sale or disposed of by means other than sale or disposal of an individually significant component.

+ References

Reference 1: http://www.xbrl.org/2003/role/presentationRef
-Publisher FASB
-Name Accounting Standards Codification
-Topic 205
-SubTopic 20
-Section 45
-Paragraph 11
-URI http://asc.fasb.org/extlink&oid=65878427&loc=SL51721533-107759

Reference 2: http://www.xbrl.org/2003/role/presentationRef
-Publisher FASB
-Name Accounting Standards Codification
-Topic 205
-SubTopic 20
-Section 50
-Paragraph 4B
-URI http://asc.fasb.org/extlink&oid=64827811&loc=SL51721665-107760

Reference 3: http://www.xbrl.org/2003/role/presentationRef
-Publisher FASB
-Name Accounting Standards Codification
-Topic 205
-SubTopic 20
-Section 50
-Paragraph 5C
-URI http://asc.fasb.org/extlink&oid=64827811&loc=SL51721675-107760

Reference 4: http://www.xbrl.org/2003/role/presentationRef
-Publisher FASB
-Name Accounting Standards Codification
-Topic 360
-SubTopic 10
-Section 50
-Paragraph 3A
-URI http://asc.fasb.org/extlink&oid=64862545&loc=SL51724579-110230

Reference 5: http://www.xbrl.org/2003/role/presentationRef
-Publisher FASB
-Name Accounting Standards Codification
-Topic 205
-SubTopic 20
-Section 50
-Paragraph 4A
-URI http://asc.fasb.org/extlink&oid=64827811&loc=SL51721663-107760

Reference 6: http://www.xbrl.org/2003/role/presentationRef
-Publisher FASB
-Name Accounting Standards Codification
-Topic 360
-SubTopic 10
-Section 50
-Paragraph 3
-URI http://asc.fasb.org/extlink&oid=64862545&loc=d3e2941-110230

Reference 7: http://www.xbrl.org/2003/role/presentationRef
-Publisher FASB
-Name Accounting Standards Codification
-Topic 205
-SubTopic 20
-Section 50
-Paragraph 1
-URI http://asc.fasb.org/extlink&oid=64827811&loc=d3e1361-107760

Reference 8: http://www.xbrl.org/2003/role/presentationRef
-Publisher FASB
-Name Accounting Standards Codification
-Topic 205
-SubTopic 20
-Section 50
-Paragraph 5B
-URI http://asc.fasb.org/extlink&oid=64827811&loc=SL51721673-107760

Reference 9: http://www.xbrl.org/2003/role/presentationRef
-Publisher FASB
-Name Accounting Standards Codification
-Topic 205
-SubTopic 20
-Section 50
-Paragraph 3A
-URI http://asc.fasb.org/extlink&oid=64827811&loc=SL51721659-107760

Reference 10: http://www.xbrl.org/2003/role/presentationRef
-Publisher FASB
-Name Accounting Standards Codification
-Topic 205
-SubTopic 20
-Section 50
-Paragraph 5A
-URI http://asc.fasb.org/extlink&oid=64827811&loc=SL51721671-107760

Reference 11: http://www.xbrl.org/2003/role/presentationRef
-Publisher FASB
-Name Accounting Standards Codification
-Topic 205
-SubTopic 20
-Section 50
-Paragraph 5D
-URI http://asc.fasb.org/extlink&oid=64827811&loc=SL51721677-107760

Reference 12: http://www.xbrl.org/2003/role/presentationRef
-Publisher FASB
-Name Accounting Standards Codification
-Topic 205
-SubTopic 20
-Section 50
-Paragraph 3
-URI http://asc.fasb.org/extlink&oid=64827811&loc=d3e1474-107760

Reference 13: http://www.xbrl.org/2003/role/presentationRef
-Publisher FASB
-Name Accounting Standards Codification
-Topic 205
-SubTopic 20
-Section 50
-Paragraph 7
-URI http://asc.fasb.org/extlink&oid=64827811&loc=SL51721683-107760

+ Details

Fair value measurements

12 Months Ended

Dec. 31, 2016

Fair value measurements [Abstract]

Fair value measurements

4. Fair value measurements

The following table represents the Company's fair value hierarchy for its financial assets and liabilities measured at fair value on a recurring basis:

	December 31, 2016
(in thousands)		Level 1		Level 2		Level 3		Total
Assets:
Investment in money market funds (1)		$	10	$	-	$	-	$	10
Total assets		$	10	$	-	$	-	$	10

Liabilities:
Contingent consideration		$	-	$	-	$	13,185	$	13,185
Total liabilities		$	-	$	-	$	13,185	$	13,185

	December 31, 2015
(in thousands)		Level 1		Level 2		Level 3		Total
Assets:
Investment in money market funds (1)		$	3,323	$	-	$	-	$	3,323
Total assets		$	3,323	$	-	$	-	$	3,323

Liabilities:
Contingent price consideration		$	-	$	-	$	25,155	$	25,155
Total liabilities		$	-	$	-	$	25,155	$	25,155

(1) Included in cash and cash equivalents in accompanying consolidated balance sheets.

As of December 31, 2016 and 2015, the Company did not have any transfers between Level 1 and Level 2 assets or liabilities.

For the year ended December 31, 2016 and 2015, the contingent consideration obligation associated with the EV-035 series of molecules and the broad spectrum antiviral platform program decreased by $5.4 million and $9.4 million, respectively. These changes are primarily due to the estimated timing and probability of success for certain development and regulatory milestones and the estimated timing and volume of potential future sales of the EV-035 series of molecules and the broad spectrum antiviral platform, which are inputs that have no observable market (Level 3), along with the novation of the Defense Threat Reduction Agency ("DTRA") contract for the EV-035 series of molecules. These decreases in the contingent consideration were classified in the Company's statement of operations as both selling, general and administrative expense and research and development expense. During 2015, the Company received novation of the DTRA contract and paid the $4.0 million milestone to Evolva in the second quarter of 2015.

For the years ended December 31, 2016 and 2015, the contingent consideration obligations associated with RSDL decreased by $5.4 million and $1.5 million, respectively. The fair value of the RSDL contingent consideration obligations decreased as a result of management's assessment of the assumed and actual achievement of future net sales, which are inputs that have no observable market (Level 3). These changes are classified in the Company's statement of operations as cost of product sales and contract manufacturing.

The following table is a reconciliation of the beginning and ending balance of the liabilities measured at fair value using significant unobservable inputs (Level 3) during the years ended December 31, 2016 and 2015.

(in thousands)
Balance at December 31, 2014	$	40,037
(Income) expense included in earnings		(10,884	)
Settlements		(4,803	)
Purchases, sales and issuances		805
Transfers in/(out) of Level 3		-
Balance at December 31, 2015	$	25,155
(Income) expense included in earnings		(10,857	)
Settlements		(1,113	)
Purchases, sales and issuances		-
Transfers in/(out) of Level 3		-
Balance at December 31, 2016	$	13,185

Separate disclosure is required for assets and liabilities measured at fair value on a recurring basis from those measured at fair value on a non-recurring basis. As of December 31, 2016, there were no assets or liabilities measured at fair value on a non-recurring basis. As of December 31, 2015, the in-process research and development asset for the EV-035 series of molecules was measured at fair value on a non-recurring basis.

- Definition

The entire disclosure for the fair value of financial instruments (as defined), including financial assets and financial liabilities (collectively, as defined), and the measurements of those instruments as well as disclosures related to the fair value of non-financial assets and liabilities. Such disclosures about the financial instruments, assets, and liabilities would include: (1) the fair value of the required items together with their carrying amounts (as appropriate); (2) for items for which it is not practicable to estimate fair value, disclosure would include: (a) information pertinent to estimating fair value (including, carrying amount, effective interest rate, and maturity, and (b) the reasons why it is not practicable to estimate fair value; (3) significant concentrations of credit risk including: (a) information about the activity, region, or economic characteristics identifying a concentration, (b) the maximum amount of loss the entity is exposed to based on the gross fair value of the related item, (c) policy for requiring collateral or other security and information as to accessing such collateral or security, and (d) the nature and brief description of such collateral or security; (4) quantitative information about market risks and how such risks are managed; (5) for items measured on both a recurring and nonrecurring basis information regarding the inputs used to develop the fair value measurement; and (6) for items presented in the financial statement for which fair value measurement is elected: (a) information necessary to understand the reasons for the election, (b) discussion of the effect of fair value changes on earnings, (c) a description of [similar groups] items for which the election is made and the relation thereof to the balance sheet, the aggregate carrying value of items included in the balance sheet that are not eligible for the election; (7) all other required (as defined) and desired information.

+ References + Details

Accounts receivable

12 Months Ended

Dec. 31, 2016

Accounts receivable [Abstract]

Accounts receivable

5. Accounts receivable

Accounts receivable consist of the following:

	December 31,
(in thousands)	2016			2015
Billed		$	90,439		$	95,735
Unbilled			48,039			18,171
Total		$	138,478		$	113,906

Unbilled accounts receivable has increased by $29.9 million due to the timing of billings to under our contract with the U.S. government related to construction activities at our Bayview site and development work associated with Ebola.

- Definition

The entire disclosure for claims held for amounts due a entity, excluding financing receivables. Examples include, but are not limited to, trade accounts receivables, notes receivables, loans receivables. Includes disclosure for allowance for credit losses.

+ References + Details

Inventories

12 Months Ended

Dec. 31, 2016

Inventories [Abstract]

Inventories

6. Inventories

Inventories consist of the following:

	December 31,
(in thousands)	2016		2015
Raw materials and supplies	$	30,687	$	21,275
Work-in-process		19,821		32,709
Finished goods		23,494		6,903
Total inventories	$	74,002	$	60,887

Property, plant and equipment

12 Months Ended

Dec. 31, 2016

Property, plant and equipment [Abstract]

Property, plant and equipment

7. Property, plant and equipment

Property, plant and equipment consist of the following:

	December 31,
(in thousands)	2016			2015
Land and improvements	$	20,340		$	16,520
Buildings, building improvements and leasehold improvements		147,130			108,908
Furniture and equipment		190,157			129,933
Software		52,564			39,683
Construction-in-progress		77,813			126,531
		488,004			421,575
Less: Accumulated depreciation and amortization		(111,556	)		(93,767	)
Total property, plant and equipment, net	$	376,448		$	327,808

For the year ended December 31, 2016, construction-in-progress primarily includes costs related to the build out of the Company's CIADM manufacturing facility. For the year ended December 31, 2015, construction-in-progress primarily included costs related to Building 55, the Company's large-scale manufacturing facility which was placed in service in June 2016.

Depreciation and amortization expense was $28.0 million, $23.7 million and $22.3 million for the years ended December 31, 2016, 2015 and 2014, respectively.

Intangible assets, in-process research and development and goodwill

12 Months Ended

Dec. 31, 2016

Intangible assets and in-process research and development [Abstract]

Intangible assets, in-process research and development

8. Intangible assets, in-process research and development and goodwill

As of October 1, 2016, the Company performed a qualitative assessment of goodwill associated with the Therapeutics and Vaccines reporting unit, Contract Manufacturing reporting unit, and the Medical Devices reporting unit. The Company completed its annual impairment assessments for its IPR&D assets and goodwill as of October 1, 2015 and determined that the fair value of the Company's IPR&D assets and reporting units was significantly in excess of carrying value. As of October 1, 2015, the Company performed a qualitative assessment of goodwill associated with the Therapeutics and Vaccines reporting unit, Contract Manufacturing reporting unit, and the Medical Devices reporting unit.

Intangible assets consisted of the following:


(in thousands)	Total
Cost basis
Balance at December 31, 2015	$	57,099
Additions		-
Balance at December 31, 2016	$	57,099

Accumulated amortization
Balance at December 31, 2015	$	(16,341	)
Amortization		(6,893	)
Balance at December 31, 2016	$	(23,234	)

Net book value at December 31, 2016	$	33,865

For the years ended December 31, 2016, 2015 and 2014, the Company recorded amortization expense of $6.9 million, $7.4 million and $7.0 million, respectively, for intangible assets, which has been recorded in operating expenses, specifically selling, general and administrative and cost of product sales and contract manufacturing. As of December 31, 2016, the weighted average amortization period remaining for intangible assets is 75 months.

Future amortization expense as of December 31, 2016 is as follows:

(in thousands)
2017	$	6,217
2018		6,217
2019		5,738
2020		5,657
2021 and beyond		10,036
Total remaining amortization	$	33,865

The following table is a summary of changes in goodwill by reporting unit:

(in thousands)	Therapeutics and vaccines		Contract manufacturing		Medical devices		Total
Cost Basis
Balance at December 31, 2015	$	24,349	$	6,736	$	9,916	$	41,001
Additions		-		-		-		-
Balance at December 31, 2016	$	24,349	$	6,736	$	9,916	$	41,001

In September 2015, the Company received data for the leading molecule in the EV-035 series of molecules, GC-072, that indicated a potential toxicity issue. The Company considered this information an indicator of impairment of the related EV-035 series of molecules IPR&D asset, and completed an impairment assessment of this asset. Based on this assessment, the Company recorded a non-cash impairment charge of $9.8 million, which is included in the Company's statement of operations as research and development expense. The remaining carrying value of the EV-035 series of molecules IPR&D asset was $0.7 million as of December 31, 2015. This remaining amount was impaired during the year ended December 31, 2016 based upon delays in the development time line. The impairment assessment was performed using the income approach which discounts expected future cash flows to present value. The projected cash flows for the EV-035 series of molecules were based on key assumptions including: estimates of revenues and operating profits considering its stage of development, the time and resources needed to complete the development and approval of the product candidate, the life of the potential commercialized product and associated risks, including the inherent difficulties and uncertainties in developing a product candidate, such as obtaining marketing approval from the FDA and other regulatory agencies, and risks related to the viability of and potential for alternative treatments in any future target markets.

As a result of the impairment of the EV-035 series of molecules IPR&D asset, the Company also performed an interim goodwill qualitative impairment assessment of the Vaccines and Therapeutics reporting unit, which contained $22.0 million of the goodwill reported on the Company's consolidated balance sheets as of September 30, 2015. Based on the assessment, the Company concluded that the goodwill was not impaired.

- Definition

The entire disclosure for the aggregate amount of goodwill and a description of intangible assets, which may include (a) for amortizable intangible assets (also referred to as finite-lived intangible assets), the carrying amount, the amount of any significant residual value, and the weighted-average amortization period, (b) for intangible assets not subject to amortization (also referred to as indefinite-lived intangible assets), the carrying amount, and (c) the amount of research and development assets acquired and written off in the period, including the line item in the income statement in which the amounts written off are aggregated, if not readily apparent from the income statement. Also discloses (a) for amortizable intangibles assets in total and by major class, the gross carrying amount and accumulated amortization, the total amortization expense for the period, and the estimated aggregate amortization expense for each of the five succeeding fiscal years, (b) for intangible assets not subject to amortization the carrying amount in total and by major class, and (c) for goodwill, in total and for each reportable segment, the changes in the carrying amount of goodwill during the period (including the aggregate amount of goodwill acquired, the aggregate amount of impairment losses recognized, and the amount of goodwill included in the gain (loss) on disposal of a reporting unit). If any part of goodwill has not been allocated to a reportable segment, discloses the unallocated amount and the reasons for not allocating. For each impairment loss recognized related to an intangible asset (excluding goodwill), discloses: (a) a description of the impaired intangible asset and the facts and circumstances leading to the impairment, (b) the amount of the impairment loss and the method for determining fair value, (c) the caption in the income statement or the statement of activities in which the impairment loss is aggregated, and (d) the segment in which the impaired intangible asset is reported. For each goodwill impairment loss recognized, discloses: (a) a description of the facts and circumstances leading to the impairment, (b) the amount of the impairment loss and the method of determining the fair value of the associated reporting unit, and (c) if a recognized impairment loss is an estimate not finalized and the reasons why the estimate is not final. May also disclose the nature and amount of any significant adjustments made to a previous estimate of an impairment loss.

+ References + Details

Long-term debt	12 Months Ended
Long-term debt	Dec. 31, 2016
Long-term debt [Abstract]
Long-term debt	9. Long-term debt On January 29, 2014, the Company issued $250.0 million aggregate principal amount of 2.875% Convertible Senior Notes due 2021 (the "Notes"). The Notes bear interest at a rate of 2.875% per year, payable semi-annually in arrears on January 15 and July 15 of each year. The Notes mature on January 15, 2021, unless earlier purchased by the Company or converted. The original conversion rate is equal to 30.8821 shares of common stock per $1,000 principal amount of notes (which is equivalent to a conversion price of approximately $32.38 per share of common stock). The conversion rate is subject to adjustment upon the occurrence of certain specified events but will not be adjusted for accrued and unpaid interest. The Company incurred approximately $8.3 million in debt issuance costs associated with the Notes, which has been capitalized on the consolidated balance sheets and is being amortized over seven years. As of August 1, 2016, certain conversion features were triggered due to the completion of the Aptevo spin-off. The conversion rate under the Notes was adjusted in accordance with the terms of the indenture. Effective August 12, 2016, the conversion rate was adjusted to 32.3860 shares of common stock per $1,000 principal amount of notes (which is equivalent to a conversion price of approximately $30.88 per share of common stock). On December 11, 2013, the Company entered into a senior secured credit agreement (the "Credit Agreement") with three lending financial institutions. The Credit Agreement provided for a revolving credit facility of up to $100.0 million through December 11, 2018 (or such earlier date required by the terms of the Credit Agreement). Under the revolving credit facility, the Company is required to pay an unused fee of approximately 0.5% annually, on a quarterly basis. In addition, during the year ended December 31, 2014, the Company expensed $1.8 million of debt issuance cost associated with the term loan facility. As of December 31, 2016 and 2015, no amounts were drawn under the revolving credit facility. The Company's payment obligations under the Credit Agreement are secured by a lien on substantially all of the Company's assets, including the stock of all of the Company's subsidiaries, and the assets of the subsidiary guarantors, including mortgages over certain of their real properties, including the Company's large-scale vaccine manufacturing facility in Lansing, Michigan and the Company's product development and manufacturing facility in Baltimore, Maryland. The Credit Agreement, as amended, contains affirmative and negative covenants customary for financings of this type. Negative covenants in the Credit Agreement limit the Company's ability to, among other things: incur indebtedness (other than the issuance of the Notes) and liens; dispose of assets; make investments including loans, advances or guarantees; and enter into certain mergers or similar transactions. The Credit Agreement also contains financial covenants, tested quarterly and in connection with any triggering events under the Credit Agreement that include the maintenance of: (1) a minimum consolidated debt service coverage ratio of 2.50 to 1.00, (2) a maximum consolidated leverage ratio for the period ending on or prior to September 30, 2014 of 4.00 to 1.00, for the measurement period ending December 31, 2014 of 3.75 to 1.00, and thereafter of 3.50 to 1.00, and (3) a minimum liquidity requirement of $50.0 million. Upon the occurrence and continuance of an event of default under the Credit Agreement, the commitments of the lenders to make loans under the Credit Agreement may be terminated and the Company's payment obligations under the Credit Agreement may be accelerated. The events of default under the Credit Agreement include, among others, subject in some cases to specified cure periods: payment defaults; inaccuracy of representations and warranties in any material respect; defaults in the observance or performance of covenants; bankruptcy and insolvency related defaults; the entry of a final judgment in excess of a threshold amount; change of control; and the invalidity of loan documents relating to the Credit Agreement. The Company was in compliance with these covenants as of December 31, 2016 and 2015. As of December 31, 2015, the Company reclassified debt issuance costs of $1.2 million and $4.9 million from prepaid expenses and other current assets and other assets, respectively, as a reduction to long-term debt as a result of the adoption of ASU No. 2015-03.

Stockholders' equity

12 Months Ended

Dec. 31, 2016

Stockholders' equity [Abstract]

Stockholders' equity

10. Stockholders' equity

Preferred stock

The Company is authorized to issue up to 15.0 million shares of preferred stock, $0.001 par value per share ("Preferred Stock"). Any Preferred Stock issued may have dividend rights, voting rights, conversion privileges, redemption characteristics, and sinking fund requirements as approved by the Company's board of directors.

Common stock

The Company currently has one class of common stock, $0.001 par value per share common stock ("Common Stock"), authorized and outstanding. The Company is authorized to issue up to 200.0 million shares of Common Stock. Holders of Common Stock are entitled to one vote for each share of Common Stock held on all matters, except as may be provided by law.

Stock options and restricted stock units

As of December 31, 2016, the Company has two stock-based employee compensation plans, the Fourth Amended and Restated Emergent BioSolutions Inc. 2006 Stock Incentive Plan (the "2006 Plan") and the Emergent BioSolutions Employee Stock Option Plan (the "2004 Plan"). The Company refers to both plans together as the "Emergent Plans." On May 19, 2016, the Company's shareholders approved the Fourth Amended and Restated Emergent BioSolutions Inc. 2006 Stock Incentive Plan, and the issuance of 3.8 million shares thereunder. In addition, the Company's shareholders approved an increase in the number of authorized shares of common stock to 200.0 million shares from 100.0 million shares.

In connection with the Separation on August 1, 2016 and in accordance with the employee matters agreement and the Emergent Plans, the Company made certain adjustments to the exercise price and number of equity awards. Continuing Emergent employees with equity awards issued prior to Distribution received an equitable adjustment reflecting a revised exercise price and number of equity awards granted. Continuing Aptevo employees who had been granted Emergent equity awards had their grants canceled and reissued as Aptevo equity awards with an adjusted exercise price.

The following is a summary of option award activity under the Emergent Plans:

	2006 Plan					2004 Plan
	Number of Shares			Weighted-Average Exercise Price		Number of Shares			Weighted-Average Exercise Price		Aggregate Intrinsic Value
Outstanding at December 31, 2015		2,964,237		$	22.73		29,699		$	10.28	$	52,119,607
Granted		411,698			33.61		-			-
Exercised		(809,638	)		19.41		(29,699	)		10.28
Forfeited		(96,293	)		26.67		-			-
Cancelled		(146,986	)		28.33		-			-
Equitable adjustment		236,313			22.90		-			-
Outstanding at December 31, 2016		2,559,331		$	22.94		-		$	-	$	25,348,245
Exercisable at December 31, 2016		1,504,855		$	19.59		-		$	-	$	19,938,451
Options expected to vest at December 31, 2016		849,184		$	27.46		-		$	-	$	4,565,548

The following is a summary of restricted stock unit award activity under the 2006 Plan:

	Number of Shares			Weighted-Average Grant Price		Aggregate Intrinsic Value
Outstanding at December 31, 2015		889,004		$	26.86	$	35,569,048
Granted		515,782			34.00
Vested		(420,599	)		24.68
Forfeited		(80,428	)		29.40
Cancelled		(107,514	)		30.90
Equitable adjustment		79,339			28.86
Outstanding at December 31, 2016		875,584		$	28.94	$	28,754,179

The weighted average remaining contractual term of options outstanding as of December 31, 2016 and 2015 was 4.0 years and 4.4 years, respectively. The weighted average remaining contractual term of options exercisable as of December 31, 2016 and 2015 was 3.2 years and 3.4 years, respectively.

The weighted average grant date fair value of options granted during the years ended December 31, 2016, 2015 and 2014 was $9.24, $8.66 and $8.84, respectively. The total intrinsic value of options exercised during the years ended December 31, 2016, 2015 and 2014 was $15.6 million, $20.2 million and $7.5 million, respectively. The total fair value of awards vested during 2016, 2015 and 2014 was $16.9 million, $14.4 million and $12.3 million, respectively. As of the year ended December 31, 2016, the total compensation cost and weighted average period over which total compensation is expected to be recognized related to unvested equity awards was $18.0 million and 1.86 years, respectively.

On July 14, 2016, the Company's board of directors authorized management to repurchase, from time to time, up to an aggregate of $50 million of the Company's common stock under a board-approved share repurchase program. The timing, amount, and price of any repurchases will be made pursuant to one or more 10b5-1 plans. The term of the board authorization of the repurchase program is until December 31, 2017. The program will permit shares to be repurchased when the Company might otherwise be precluded from doing so under insider trading laws. The repurchase program may be suspended or discontinued at any time. Any repurchased shares will be available for use in connection with the Company's stock plans and for other corporate purposes. As of December 31, 2016, the Company has neither implemented a repurchase plan nor repurchased any shares under this program.

Stock-based compensation expense was recorded in the following financial statement line items:

	Years ended December 31,
(in thousands)	2016		2015		2014
Cost of product sales	$	997	$	1,183	$	1,145
Research and development		2,297		2,324		2,779
Selling, general and administrative		14,062		11,234		7,830
Continuing operations		17,356		14,741		11,754
Discontinued operations		1,121		1,107		1,075
Total stock-based compensation expense	$	18,477	$	15,848	$	12,829

- Definition

The entire disclosure for shareholders' equity comprised of portions attributable to the parent entity and noncontrolling interest, including other comprehensive income. Includes, but is not limited to, balances of common stock, preferred stock, additional paid-in capital, other capital and retained earnings, accumulated balance for each classification of other comprehensive income and amount of comprehensive income.

+ References

Reference 1: http://www.xbrl.org/2003/role/presentationRef
-Publisher FASB
-Name Accounting Standards Codification
-Topic 310
-SubTopic 10
-Section S99
-Paragraph 4
-Subparagraph (SAB Topic 4.E)
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-Name Accounting Standards Codification
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Reference 14: http://www.xbrl.org/2003/role/presentationRef
-Publisher FASB
-Name Accounting Standards Codification
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-URI http://asc.fasb.org/extlink&oid=6521494

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+ Details

Income taxes

12 Months Ended

Dec. 31, 2016

Income taxes [Abstract]

Income taxes

11. Income taxes

Significant components of the provisions for income taxes attributable to operations consist of the following:

	Year ended December 31,
(in thousands)	2016			2015			2014
Current
Federal	$	29,244		$	38,957		$	22,988
State		2,331			2,221			959
International		1,002			2,029			828
Total current		32,577			43,207			24,775
Deferred
Federal		9,979			(119	)		3,332
State		(272	)		(111	)		209
International		(5,587	)		1,323			1,612
Total deferred		4,120			1,093			5,153
Total provision for income taxes	$	36,697		$	44,300		$	29,928

The Company's net deferred tax asset (liability) consists of the following:

	December 31,
(in thousands)	2016			2015
Federal losses carryforward	$	4,130		$	5,394
State losses carryforward		13,682			12,751
Research and development carryforward		3,647			3,545
Scientific research and experimental development credit carryforward		16,594			25,771
Intangible assets		-			5,792
Stock compensation		8,389			9,391
Foreign deferrals		58,647			80,920
Inventory reserves		2,273			3,754
Other		5,569			8,484
Deferred tax asset		112,931			155,802
Fixed assets		(30,728	)		(31,925	)
Intangible assets		(5,882	)		(4,760	)
Other		(16,047	)		(17,192	)
Deferred tax liability		(52,657	)		(53,877	)
Valuation allowance		(54,178	)		(90,639	)
Net deferred tax (liabilities)/ asset	$	6,096		$	11,286

As of December 31, 2016, the Company currently has approximately $11.8 million ($4.1 million tax effected) in net operating loss carryforwards along with $3.7 million in research and development tax credit carryforwards for U.S. federal tax purposes that will begin to expire in 2026 and 2023, respectively. The U.S. federal tax carryforwards are recorded with no valuation allowance. The Company has $255.1 million ($13.7 million tax effected) in state net operating loss carryforwards, primarily in Maryland, that will begin to expire in 2018. The U.S. state tax loss carryforwards are recorded with a valuation allowance of $191.7 million ($10.3 million tax effected). The Company has approximately $170.3 million ($43.9 million tax effected) in net operating losses from foreign jurisdictions (excluding Canada) that will have an indefinite life unless the foreign entities have a change in the nature or conduct of the business in the three years following a change in ownership. A valuation allowance in respect to these foreign losses has been recorded in the amount of $43.9 million. The Company has approximately $43.6 million ($11.7 million tax effected) in Canadian loss carryforwards which are recorded with no valuation allowance. The Company currently has approximately $0.5 million of Canadian federal scientific research and experimental development credit carryforwards that will begin to expire in 2027. In addition, the Company has approximately $16.1 million in Manitoba scientific research and experimental development credit carryforwards that will begin to expire in 2024. The use of any of these net operating losses and research and development tax credit carryforwards may be restricted due to changes in the Company's ownership.

The provision for income taxes differs from the amount of taxes determined by applying the U.S. federal statutory rate to loss before provision for income taxes as a result of the following:

	Year ended December 31,
(in thousands)	2016			2015			2014
US	$	63,330		$	117,385		$	76,909
International		35,891			18,331			7,285
Earnings before taxes on income		99,221			135,716			84,194

Federal tax at statutory rates	$	34,738		$	47,475		$	29,468
State taxes, net of federal benefit		529			852			650
Impact of foreign operations		(9,937	)		(1,640	)		(1,176	)
Change in valuation allowance		10,458			(950	)		1,091
Effect of foreign rates		(720	)		-			-
Tax credits		(1,572	)		(2,088	)		(1,743	)
Other differences		1,823			733			126
Permanent differences		1,378			(82	)		1,512
Provision for income taxes	$	36,697		$	44,300		$	29,928

The effective annual tax rate for the years ended December 31, 2016, 2015 and 2014 was 37%, 33% and 36%, respectively.

The increase in the effective annual tax rate in 2016 is primarily related to tax on the sale, within the Company's consolidated group, of assets from Canadian subsidiaries to U.S. subsidiaries in preparation of the spin-off of Aptevo, and a valuation allowance charge recorded in its continuing operations related to Aptevo deferred tax assets prior to the distribution. The Company determined that upon spin-off, the deferred tax assets of Aptevo would be unrealizable. The increase in the effective annual tax rate as a result of the above was partially offset by a release of valuation allowances associated with Canadian Scientific Research and Experimental Development tax credits. Finally, the Company had a shift in the jurisdictional mix of earnings in the current year which contributed to the change in the effective annual tax rate.

The Company recognizes interest in interest expense and recognizes potential penalties related to unrecognized tax benefits in selling, general and administrative expense. Of the total unrecognized tax benefits recorded at December 31, 2016 and 2015, $0.5 million and $0.3 million, respectively, is classified as a current liability and $1.3 million and $1.1 million, respectively, is classified as a non-current liability on the balance sheet.

The table below presents the gross unrecognized tax benefits activity for 2016, 2015 and 2014:

(in thousands)
Gross unrecognized tax benefits at December 31, 2013	$	1,121
Increases for tax positions for prior years		150
Decreases for tax positions for prior years		-
Increases for tax positions for current year		102
Settlements		-
Lapse of statute of limitations		(125	)
Gross unrecognized tax benefits at December 31, 2014		1,248
Increases for tax positions for prior years		150
Decreases for tax positions for prior years		-
Increases for tax positions for current year		59
Settlements		-
Lapse of statute of limitations		-
Gross unrecognized tax benefits at December 31, 2015		1,457
Increases for tax positions for prior years		5
Decreases for tax positions for prior years		-
Increases for tax positions for current year		299
Settlements		-
Lapse of statute of limitations		-
Gross unrecognized tax benefits at December 31, 2016	$	1,761

When resolved, substantially all of these reserves would impact the effective tax rate.

The Company's federal and state income tax returns for the tax years 2011 to 2015 remain open to examination. The Company's tax returns in the United Kingdom remain open to examination for the tax years 2007 to 2015, and tax returns in Germany remain open indefinitely. The Company's tax returns for Canada remains open to examination for the tax years 2009 to 2015.

As of December 31, 2016, the Company's 2011 and 2012 federal income tax returns are under audit.

Purchase commitment	12 Months Ended
Purchase commitment	Dec. 31, 2016
Purchase commitment [Abstract]
Purchase commitment	12. Purchase commitment During 2014 the Company entered into a contract with Norwood Laboratories Inc. ("Norwood") to purchase $15.2 million of raw materials related to the Company's RSDL product. For the years ended December 31, 2016, 2015 and 2014, the Company purchased $4.5 million, $6.2 million and $1.5 million, respectively, of materials under this commitment.

401(k) savings plan	12 Months Ended
401(k) savings plan	Dec. 31, 2016
401(k) savings plan [Abstract]
401(k) savings plan	13. 401(k) savings plan The Company has established a defined contribution savings plan under Section 401(k) of the Internal Revenue Code. The 401(k) Plan covers substantially all U.S. employees. Under the 401(k) Plan, employees may make elective salary deferrals. The Company currently provides for matching of qualified deferrals up to 50% of the first 6% of the employee's salary. During the years ended December 31, 2016, 2015, and 2014, the Company made matching contributions of approximately $2.5 million, $2.2 million and $2.1 million, respectively.

Related party transactions	12 Months Ended
Related party transactions	Dec. 31, 2016
Related party transactions [Abstract]
Related party transactions	14. Related party transactions In November 2015, the Company entered into a consulting arrangement with a member of the Company's Board of Directors, amended in July 2016, to provide assistance in connection with the planned spin-off of Aptevo. The total compensation under the agreement was approximately $0.2 million per year. The consulting agreement terminated on August 1, 2016. The Company entered into an agreement in February 2009 with an entity controlled by family members of the Company's Executive Chairman to market and sell BioThrax. The agreement was effective as of November 2008 and requires payment based on a percentage of net sales of biodefense products of 17.5% in Saudi Arabia and 15% in Qatar and United Arab Emirates, and reimbursement of certain expenses. No expenses were incurred under this agreement during 2016, 2015 and 2014.

Earnings per share

12 Months Ended

Dec. 31, 2016

Earnings per share [Abstract]

Earnings per share

15. Earnings per share

The following table presents the calculation of basic and diluted net income per share:

	Years ended December 31,
(in thousands, except share and per share data)	2016			2015			2014
Numerator:
Net income from continuing operations	$	62,524		$	91,416		$	54,266
Interest expense, net of tax		3,255			3,019			2,879
Amortization of debt issuance costs, net of tax		781			868			735
Net income, adjusted from continuing operations		66,560			95,303			57,880
Net loss from discontinued operations		(10,748	)		(28,546	)		(17,525	)
Net income, adjusted	$	55,812		$	66,757		$	40,355

Denominator:
Weighted-average number of shares-basic		40,184,159			38,595,435			37,344,891
Dilutive securities-equity awards		1,054,453			939,882			737,391
Dilutive securities-convertible debt		8,096,500			7,720,525			7,720,525
Weighted-average number of shares-diluted		49,335,112			47,255,842			45,802,807

Net income per share-basic from continuing operations	$	1.56		$	2.37		$	1.45
Net loss per share-basic from discontinued operations		(0.27	)		(0.74	)		(0.47	)
Net income per share-basic	$	1.29		$	1.63		$	0.98

Net income per share-diluted from continuing operations	$	1.35		$	2.02		$	1.26
Net loss per share-diluted from discontinued operations		(0.22	)		(0.61	)		(0.38	)
Net income per share-diluted	$	1.13		$	1.41		$	0.88

For the year ending December 31, 2016 and 2015, substantially all of the outstanding stock options to purchase shares of common stock were included in the calculation of diluted earnings per share. For the years ending December 31, 2014, outstanding stock options to purchase approximately 1.4 million shares of common stock, respectively, are not considered in the diluted earnings per share calculation because the exercise price of these options is greater than the average per share closing price during the year and their effect would be anti-dilutive.

Restructuring

12 Months Ended

Dec. 31, 2016

Restructuring [Abstract]

Restructuring

16. Restructuring

In August 2016, the Company adopted a plan to restructure and reprioritize the operations of one of our facilities at the Emergent BioDefense Operations Lansing LLC ("EBOL") site due to the Company's large-scale manufacturing facility at EBOL commencing manufacturing operations. Severance and other related costs and asset-related charges are reflected within the Company's consolidated statement of income as a component of selling, general and administrative expense.

The Company has completed this restructuring. The costs of the restructuring as of December 31, 2016 are detailed below:

	Incurred in		Inception to Date		Total Expected
(in thousands)	2016		Costs Incurred		to be Incurred
Termination benefits	$	5,246	$	5,246	$	5,287
Abandonment of equipment		3,749		3,749		3,749
Other costs		691		691		691
Total	$	9,686	$	9,686	$	9,727

During the years ended December 31, 2016, the Company abandoned certain equipment and associated assets at its EBOL facility related to the manufacturing process at Building 12 ("manufacturing process") asset group. The Company recorded a charge for the manufacturing process asset group of $3.7 million. The additional expense is classified in the Company's statements of operations as selling, general and administrative expense.

The following is a summary of the activity for the liabilities related to the EBOL restructuring:

	Termination
(in thousands)	Benefits
Balance at December 31, 2015	$	-
Expenses incurred		5,246
Amount paid		(889	)
Other adjustments		-
Balance at December 31, 2016	$	4,357

In addition to the above restructuring costs, the Company also recorded a charge of $2.0 million during the year ended December 31, 2016 related to retention payments for certain employees at the EBOL site.

Segment information	12 Months Ended
Segment information	Dec. 31, 2016
Segment information [Abstract]
Segment information	17. Segment information On August 6, 2015, the Company announced its plan to separate into two independent publicly-traded companies. In anticipation of the spin-off, the Company realigned certain components of its biosciences business to the new Aptevo segment to be consistent with how the CODM allocates resources and makes decisions about the operations of the Company. Effective January 1, 2016, the Company changed its segment presentation to reflect this new structure, and recast all prior periods presented to conform to the new presentation. On August 1, 2016, the Company completed the spin-off of Aptevo. The results of operations and financial position of Aptevo are reflected as discontinued operations for all periods presented through the date of the spin-off. For financial reporting purposes, in the periods following the spin-off of Aptevo, the Company reports financial information for one business segment. For the years ended December 31, 2016, 2015 and 2014, the Company's revenues from the United States comprised 96%, 98% and 96%, respectively, of total revenues. For the years ended December 31, 2016, 2015 and 2014, product revenues from BioThrax comprised approximately 80%, 89% and 87%, respectively, of total product revenues. As of December 31, 2016, 2015 and 2014, there were no other product sales in excess of 10% of total product sales revenues. For years ended December 31, 2016 and 2015, the Company had long-lived assets outside of the United States of approximately $28.4 million and $25.8 million, respectively, which are primarily located within Canada.

- Definition

The entire disclosure for reporting segments including data and tables. Reportable segments include those that meet any of the following quantitative thresholds a) it's reported revenue, including sales to external customers and intersegment sales or transfers is 10 percent or more of the combined revenue, internal and external, of all operating segments b) the absolute amount of its reported profit or loss is 10 percent or more of the greater, in absolute amount of 1) the combined reported profit of all operating segments that did not report a loss or 2) the combined reported loss of all operating segments that did report a loss c) its assets are 10 percent or more of the combined assets of all operating segments.

+ References

Reference 1: http://www.xbrl.org/2003/role/presentationRef
-Publisher FASB
-Name Accounting Standards Codification
-Topic 280
-SubTopic 10
-Section 50
-Paragraph 34
-URI http://asc.fasb.org/extlink&oid=68060357&loc=d3e8981-108599

Reference 2: http://www.xbrl.org/2003/role/presentationRef
-Publisher FASB
-Name Accounting Standards Codification
-Topic 280
-SubTopic 10
-Section 50
-Paragraph 41
-URI http://asc.fasb.org/extlink&oid=68060357&loc=d3e9038-108599

Reference 3: http://www.xbrl.org/2003/role/presentationRef
-Publisher FASB
-Name Accounting Standards Codification
-Topic 280
-SubTopic 10
-Section 50
-Paragraph 33
-URI http://asc.fasb.org/extlink&oid=68060357&loc=d3e8971-108599

Reference 4: http://www.xbrl.org/2003/role/presentationRef
-Publisher FASB
-Name Accounting Standards Codification
-Topic 280
-SubTopic 10
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-URI http://asc.fasb.org/extlink&oid=68060357&loc=d3e8595-108599

Reference 5: http://www.xbrl.org/2003/role/presentationRef
-Publisher FASB
-Name Accounting Standards Codification
-Topic 280
-SubTopic 10
-Section 50
-Paragraph 1
-URI http://asc.fasb.org/extlink&oid=68060357&loc=d3e8380-108599

Reference 6: http://www.xbrl.org/2003/role/presentationRef
-Publisher FASB
-Name Accounting Standards Codification
-Topic 280
-SubTopic 10
-Section 50
-Paragraph 32
-URI http://asc.fasb.org/extlink&oid=68060357&loc=d3e8933-108599

Reference 7: http://www.xbrl.org/2003/role/presentationRef
-Publisher FASB
-Name Accounting Standards Codification
-Topic 280
-SubTopic 10
-Section 50
-Paragraph 26
-URI http://asc.fasb.org/extlink&oid=68060357&loc=d3e8844-108599

Reference 8: http://www.xbrl.org/2003/role/presentationRef
-Publisher FASB
-Name Accounting Standards Codification
-Topic 280
-SubTopic 10
-Section 50
-Paragraph 35
-URI http://asc.fasb.org/extlink&oid=68060357&loc=d3e8984-108599

Reference 9: http://www.xbrl.org/2003/role/presentationRef
-Publisher FASB
-Name Accounting Standards Codification
-Topic 280
-SubTopic 10
-Section 50
-Paragraph 40
-URI http://asc.fasb.org/extlink&oid=68060357&loc=d3e9031-108599

Reference 10: http://www.xbrl.org/2003/role/presentationRef
-Publisher FASB
-Name Accounting Standards Codification
-Topic 280
-SubTopic 10
-Section 50
-Paragraph 42
-URI http://asc.fasb.org/extlink&oid=68060357&loc=d3e9054-108599

Reference 11: http://www.xbrl.org/2003/role/presentationRef
-Publisher FASB
-Name Accounting Standards Codification
-Topic 280
-SubTopic 10
-Section 50
-Paragraph 10
-URI http://asc.fasb.org/extlink&oid=68060357&loc=d3e8538-108599

Reference 12: http://www.xbrl.org/2003/role/presentationRef
-Publisher FASB
-Name Accounting Standards Codification
-Topic 280
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-Paragraph 29
-URI http://asc.fasb.org/extlink&oid=68060357&loc=d3e8864-108599

Reference 13: http://www.xbrl.org/2003/role/presentationRef
-Publisher FASB
-Name Accounting Standards Codification
-Topic 280
-SubTopic 10
-Section 50
-Paragraph 31
-URI http://asc.fasb.org/extlink&oid=68060357&loc=d3e8924-108599

Reference 14: http://www.xbrl.org/2003/role/presentationRef
-Publisher FASB
-Name Accounting Standards Codification
-Topic 280
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-Section 50
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-URI http://asc.fasb.org/extlink&oid=68060357&loc=d3e8906-108599

+ Details

Quarterly financial data (unaudited)

12 Months Ended

Dec. 31, 2016

Quarterly financial data (unaudited) [Abstract]

Quarterly financial data (unaudited)

18. Quarterly financial data (unaudited)

Quarterly financial information for the years ended December 31, 2016 and 2015 is presented in the following tables:

	Quarter Ended
(in thousands, except per share data)	March 31,			June 30,			September 30,			December 31,
2016:
Revenue	$	102,964		$	91,241		$	142,914		$	151,663
Income (loss) from operations		21,157			(2,042	)		35,478			50,929
Net income (loss) from continuing operations		11,889			(2,042	)		20,388			32,289
Net income (loss) from discontinued operations (1)		(7,898	)		(8,905	)		952			5,103
Net income (loss)		3,991			(10,947	)		21,340			37,392

Net income (loss) per share from continuing operations-basic	$	0.30		$	(0.05	)	$	0.50		$	0.80
Net income (loss) per share from discontinued operations-basic		(0.20	)		(0.22	)		0.02			0.13
Net income (loss) per share-basic	$	0.10		$	(0.27	)	$	0.52		$	0.93

Net income (loss) per share from continuing operations-diluted	$	0.26		$	(0.05	)	$	0.43		$	0.67
Net income (loss) per share from discontinued operations-diluted		(0.16	)		(0.22	)		0.02			0.10
Net income (loss) per share-diluted	$	0.10		$	(0.27	)	$	0.45		$	0.77

2015
Revenue	$	52,147		$	119,022		$	158,378		$	159,784
Income (loss) from operations		(21,895	)		35,104			63,159			65,146
Net income (loss) from continuing operations		(15,728	)		22,565			42,088			42,491
Net loss from discontinued operations		(5,792	)		(8,465	)		(5,145	)		(9,144	)
Net income (loss)		(21,520	)		14,100			36,943			33,347

Net income (loss) per share from continuing operations-basic	$	(0.42	)	$	0.59		$	1.08		$	1.08
Net loss per share from discontinued operations-basic		(0.15	)		(0.22	)		(0.14	)		(0.23	)
Net income (loss) per share-basic	$	(0.57	)	$	0.37		$	0.94		$	0.85

Net income (loss) per share from continuing operations-diluted	$	(0.42	)	$	0.50		$	0.90		$	0.90
Net loss per share from discontinued operations-diluted		(0.15	)		(0.18	)		(0.11	)		(0.19	)
Net income (loss) per share-diluted	$	(0.57	)	$	0.32		$	0.79		$	0.71

(1) Reflects a change in estimate attributed to higher pretax income within continuing operations. According to the ordering rules of intraperiod tax allocation, the residual amount of change after determining the effective rate for continuing operations is allocated to discontinued operations.

Litigation	12 Months Ended
Litigation	Dec. 31, 2016
Litigation [Abstract]
Litigation	19. Litigation On July 19, 2016, Plaintiff William Sponn, or Sponn, filed a putative class action complaint in the United States District Court for the District of Maryland on behalf of purchasers of the Company's common stock between January 11, 2016 and June 21, 2016, inclusive, or the Class Period, seeking to pursue remedies under the Securities Exchange Act of 1934 against the Company and certain of its senior officers and directors, collectively, the Defendants. The complaint alleges, among other things, that the Company made materially false and misleading statements about the government's demand for BioThrax and expectations that the Company's five-year exclusive procurement contract with HHS would be renewed and omitted certain material facts. Sponn is seeking unspecified damages, including legal costs. On October 25, 2016 the Court added City of Cape Coral Municipal Firefighters' Retirement Plan and City of Sunrise Police Officers' Retirement Plan as plaintiffs and appointed them Lead Plaintiffs and Robins Geller Rudman & Dowd LLP as Lead Counsel. On December 27, 2016 the plaintiffs filed an amended complaint that cites the same class period, names the same defendants and makes similar allegations to the original complaint. The Company filed a Motion to Dismiss on February 27, 2017. The Defendants believe that the allegations in the complaint are without merit and intend to defend themselves vigorously against those claims. As of the date of this filing, the range of potential loss cannot be determined or estimated.

Summary of significant accounting policies (Policies)

12 Months Ended

Dec. 31, 2016

Summary of significant accounting policies [Abstract]

Basis of presentation and consolidation

Use of estimates

Cash and cash equivalents

Fair value of measurements

Level 1 —

Observable inputs for identical assets or liabilities such as quoted prices in active markets;

Level 2 —

Inputs other than quoted prices in active markets that are either directly or indirectly observable; and

Level 3 —

Unobservable inputs in which little or no market data exists, which are therefore developed by the Company using estimates and assumptions that reflect those that a market participant would use.

Significant customers and accounts receivable

Concentrations of credit risk

Concentrations of credit risk and uncertainties

Inventories

Property, plant and equipment

Property, plant and equipment are stated at cost. Depreciation is computed using the straight-line method over the following estimated useful lives:

Buildings	31-39 years
Building improvements	10-39 years
Furniture and equipment	3-15 years
Software	3-7 years or product life
Leasehold improvements	Lesser of the asset life or lease term

Income taxes

Revenue recognition

The Company recognizes revenues from product sales and contract manufacturing if four basic criteria have been met:



there is persuasive evidence of an arrangement;



delivery has occurred or title has passed to the Company's customer;



the fee is fixed or determinable; and



collectability is reasonably assured.

BAT product sales upon delivery to the SNS;

stability testing based on the required testing schedule of the product;

extended product expiry based on achievement of the extension;

horse maintenance based on a per horse basis; and

plasma collection on a per liter basis.

VIGIV and Anthrasil product sales upon delivery to the CDC;

stability testing based on the required testing schedule of the product;

extended product expiry based on achievement of the extension; and

plasma collection on a per liter basis.

Mergers and Acquisitions

Impairment of long-lived assets

In process research and development and long-lived assets

Goodwill

Contingent purchase consideration obligations

Contingent Consideration

Research and development

We expense research and development costs as incurred. Our research and development expenses consist primarily of:

personnel-related expenses;

costs of contract manufacturing services for clinical trial material; and

costs of materials used in clinical trials and research and development.

Earnings per share

The Company calculates basic earnings per share by dividing net income by the weighted average number of shares of common stock outstanding during the period.

Accounting for stock-based compensation

	Year Ended December 31,
		2016	2015	2014
Expected dividend yield		0%	0%	0%
Expected volatility		31-33%	34-35%	35-38%
Risk-free interest rate		0.93-1.22%	1.27-1.61%	1.14-1.65%
Expected average life of options		4.3 years	4.3 years	4.5 years



Expected dividend yield — the Company does not pay regular dividends on its common stock and does not anticipate paying any dividends in the foreseeable future.



Risk-free interest rate — the range of U.S. Treasury rates with a term that most closely resembles the expected life of the option as of the date on which the option is granted.



Recently issued and adopted accounting standards

There are no other recently issued accounting pronouncements that are expected to have a material effect on the Company's financial position, results of operations or cash flows.

Summary of significant accounting policies (Tables)

12 Months Ended

Dec. 31, 2016

Summary of significant accounting policies [Abstract]

Estimated useful lives of property, plant and equipment

Property, plant and equipment are stated at cost. Depreciation is computed using the straight-line method over the following estimated useful lives:

Buildings	31-39 years
Building improvements	10-39 years
Furniture and equipment	3-15 years
Software	3-7 years or product life
Leasehold improvements	Lesser of the asset life or lease term

Assumptions used in valuing stock options granted

	Year Ended December 31,
		2016	2015	2014
Expected dividend yield		0%	0%	0%
Expected volatility		31-33%	34-35%	35-38%
Risk-free interest rate		0.93-1.22%	1.27-1.61%	1.14-1.65%
Expected average life of options		4.3 years	4.3 years	4.5 years

Discontinued operations (Tables)

12 Months Ended

Dec. 31, 2016

Discontinued operations [Abstract]

Summary of assets and liabilities presented as discontinued operations

The following table represents the carrying value of Aptevo's assets and liabilities distributed as part of the Separation on August 1, 2016:

(in thousands)	August 1, 2016

Assets:
Cash and cash equivalents	$	45,000
Accounts receivable, net		4,465
Inventories		11,959
Note receivable		20,000
Other current assets		4,870
Current assets of discontinued operations		86,294

Property, plant and equipment, net		6,128
In-process research and development		41,800
Intangible assets, net		15,402
Goodwill		13,902
Non-current assets of discontinued operations		77,232
Total assets of discontinued operations	$	163,526

Liabilities:
Accounts payable	$	6,285
Accrued expenses and other current liabilities		64
Accrued compensation		2,456
Contingent consideration		191
Provisions for chargebacks		2,341
Deferred revenue, current portion		433
Current liabilities of discontinued operations		11,770

Deferred revenue, net of current portion		3,232
Other liabilities		91
Non-current liabilities of discontinued operations		3,323
Total liabilities of discontinued operations	$	15,093

The following table represents Aptevo's assets and liabilities presented as discontinued operations and classified as held-for-disposition as of December 31, 2015:

(in thousands)	December 31, 2015

Assets:
Cash and cash equivalents	$	4,492
Accounts receivable, net		6,861
Inventories		16,049
Prepaid expenses and other current assets		1,880
Current assets of discontinued operations		29,282

Property, plant and equipment, net		4,046
In-process research and development		41,800
Intangible assets, net		16,617
Goodwill		13,902
Non-current assets of discontinued operations		76,365
Total assets of discontinued operations	$	105,647

Liabilities:
Accounts payable	$	8,134
Accrued expenses and other current liabilities		22
Accrued compensation		2,684
Contingent consideration, current portion		306
Provisions for chargebacks		2,238
Deferred revenue, current portion		3,964
Current liabilities of discontinued operations		17,348

Deferred revenue, net of current portion		3,163
Other liabilities		71
Non-current liabilities of discontinued operations		3,234
Total liabilities of discontinued operations	$	20,582

Summarized results of discontinued operations included in consolidated statements of income

The following table summarizes results from discontinued operations of Aptevo included in the consolidated statements of operations:

	Years ended December 31,
(in thousands)	2016			2015			2014

Revenues:
Product sales	$	21,183		$	27,947		$	30,036
Collaborations		187			5,511			15,636
Total revenues		21,370			33,458			45,672

Operating expense:
Cost of product sales		11,556			16,809			16,449
Research and development		18,024			34,811			46,108
Selling, general and administrative		23,792			27,313			14,248
Loss from operations		(32,002	)		(45,475	)		(31,133	)

Other income (expense), net:		(41	)		(472	)		-

Loss from discontinued operations before benefit from income taxes		(32,043	)		(45,947	)		(31,133	)
Benefit from income taxes		(21,295	)		(17,401	)		(13,608	)
Net loss from discontinued operations	$	(10,748	)	$	(28,546	)	$	(17,525	)

Summary of disposal groups including discontinued operations cash flows

The following table summarizes the cash flows of Aptevo included in the years ended December 31, 2016, 2015 and 2014 consolidated statements of cash flows:

	Years ended December 31,
(in thousands)	2016			2015			2014
Net cash (used in) provided by operating activities	$	(10,299	)	$	(12,716	)	$	(14,683	)
Net cash used in investing activities		(1,926	)		(1,518	)		(48,822	)
Net cash provided by (used in) financing activities		7,733			15,012			67,219

Net increase (decrease) in cash and cash equivalents	$	(4,492	)	$	778		$	3,714

Fair value measurements (Tables)

12 Months Ended

Dec. 31, 2016

Fair value measurements [Abstract]

Fair Value Hierarchy for Financial Assets and Liabilities Measured at Fair Value on a Recurring Basis

The following table represents the Company's fair value hierarchy for its financial assets and liabilities measured at fair value on a recurring basis:

	December 31, 2016
(in thousands)		Level 1		Level 2		Level 3		Total
Assets:
Investment in money market funds (1)		$	10	$	-	$	-	$	10
Total assets		$	10	$	-	$	-	$	10

Liabilities:
Contingent consideration		$	-	$	-	$	13,185	$	13,185
Total liabilities		$	-	$	-	$	13,185	$	13,185

	December 31, 2015
(in thousands)		Level 1		Level 2		Level 3		Total
Assets:
Investment in money market funds (1)		$	3,323	$	-	$	-	$	3,323
Total assets		$	3,323	$	-	$	-	$	3,323

Liabilities:
Contingent price consideration		$	-	$	-	$	25,155	$	25,155
Total liabilities		$	-	$	-	$	25,155	$	25,155

(1) Included in cash and cash equivalents in accompanying consolidated balance sheets.

Reconciliation of Liabilities Measured at Fair Value Using Significant Unobservable Inputs (Level 3)

(in thousands)
Balance at December 31, 2014	$	40,037
(Income) expense included in earnings		(10,884	)
Settlements		(4,803	)
Purchases, sales and issuances		805
Transfers in/(out) of Level 3		-
Balance at December 31, 2015	$	25,155
(Income) expense included in earnings		(10,857	)
Settlements		(1,113	)
Purchases, sales and issuances		-
Transfers in/(out) of Level 3		-
Balance at December 31, 2016	$	13,185

Accounts receivable (Tables)

12 Months Ended

Dec. 31, 2016

Accounts receivable [Abstract]

Accounts receivable

Accounts receivable consist of the following:

	December 31,
(in thousands)	2016			2015
Billed		$	90,439		$	95,735
Unbilled			48,039			18,171
Total		$	138,478		$	113,906

Inventories (Tables)

12 Months Ended

Dec. 31, 2016

Inventories [Abstract]

Inventories

Inventories consist of the following:

	December 31,
(in thousands)	2016		2015
Raw materials and supplies	$	30,687	$	21,275
Work-in-process		19,821		32,709
Finished goods		23,494		6,903
Total inventories	$	74,002	$	60,887

Property, plant and equipment (Tables)

12 Months Ended

Dec. 31, 2016

Property, plant and equipment [Abstract]

Property, plant and equipment

Property, plant and equipment consist of the following:

	December 31,
(in thousands)	2016			2015
Land and improvements	$	20,340		$	16,520
Buildings, building improvements and leasehold improvements		147,130			108,908
Furniture and equipment		190,157			129,933
Software		52,564			39,683
Construction-in-progress		77,813			126,531
		488,004			421,575
Less: Accumulated depreciation and amortization		(111,556	)		(93,767	)
Total property, plant and equipment, net	$	376,448		$	327,808

Intangible assets, in-process research and development and goodwill (Tables)

12 Months Ended

Dec. 31, 2016

Intangible assets and in-process research and development [Abstract]

Intangible Assets

Intangible assets consisted of the following:


(in thousands)	Total
Cost basis
Balance at December 31, 2015	$	57,099
Additions		-
Balance at December 31, 2016	$	57,099

Accumulated amortization
Balance at December 31, 2015	$	(16,341	)
Amortization		(6,893	)
Balance at December 31, 2016	$	(23,234	)

Net book value at December 31, 2016	$	33,865

Future Amortization Expense

Future amortization expense as of December 31, 2016 is as follows:

(in thousands)
2017	$	6,217
2018		6,217
2019		5,738
2020		5,657
2021 and beyond		10,036
Total remaining amortization	$	33,865

Goodwill

The following table is a summary of changes in goodwill by reporting unit:

(in thousands)	Therapeutics and vaccines		Contract manufacturing		Medical devices		Total
Cost Basis
Balance at December 31, 2015	$	24,349	$	6,736	$	9,916	$	41,001
Additions		-		-		-		-
Balance at December 31, 2016	$	24,349	$	6,736	$	9,916	$	41,001

Stockholders' equity (Tables)

12 Months Ended

Dec. 31, 2016

Stockholders' equity [Abstract]

Option award activity

The following is a summary of option award activity under the Emergent Plans:

	2006 Plan					2004 Plan
	Number of Shares			Weighted-Average Exercise Price		Number of Shares			Weighted-Average Exercise Price		Aggregate Intrinsic Value
Outstanding at December 31, 2015		2,964,237		$	22.73		29,699		$	10.28	$	52,119,607
Granted		411,698			33.61		-			-
Exercised		(809,638	)		19.41		(29,699	)		10.28
Forfeited		(96,293	)		26.67		-			-
Cancelled		(146,986	)		28.33		-			-
Equitable adjustment		236,313			22.90		-			-
Outstanding at December 31, 2016		2,559,331		$	22.94		-		$	-	$	25,348,245
Exercisable at December 31, 2016		1,504,855		$	19.59		-		$	-	$	19,938,451
Options expected to vest at December 31, 2016		849,184		$	27.46		-		$	-	$	4,565,548

Restricted stock units activity

The following is a summary of restricted stock unit award activity under the 2006 Plan:

	Number of Shares			Weighted-Average Grant Price		Aggregate Intrinsic Value
Outstanding at December 31, 2015		889,004		$	26.86	$	35,569,048
Granted		515,782			34.00
Vested		(420,599	)		24.68
Forfeited		(80,428	)		29.40
Cancelled		(107,514	)		30.90
Equitable adjustment		79,339			28.86
Outstanding at December 31, 2016		875,584		$	28.94	$	28,754,179

Allocated stock-based compensation expense

Stock-based compensation expense was recorded in the following financial statement line items:

	Years ended December 31,
(in thousands)	2016		2015		2014
Cost of product sales	$	997	$	1,183	$	1,145
Research and development		2,297		2,324		2,779
Selling, general and administrative		14,062		11,234		7,830
Continuing operations		17,356		14,741		11,754
Discontinued operations		1,121		1,107		1,075
Total stock-based compensation expense	$	18,477	$	15,848	$	12,829

Income taxes (Tables)

12 Months Ended

Dec. 31, 2016

Income taxes [Abstract]

Components of the provision for income taxes attributable to operations

Significant components of the provisions for income taxes attributable to operations consist of the following:

	Year ended December 31,
(in thousands)	2016			2015			2014
Current
Federal	$	29,244		$	38,957		$	22,988
State		2,331			2,221			959
International		1,002			2,029			828
Total current		32,577			43,207			24,775
Deferred
Federal		9,979			(119	)		3,332
State		(272	)		(111	)		209
International		(5,587	)		1,323			1,612
Total deferred		4,120			1,093			5,153
Total provision for income taxes	$	36,697		$	44,300		$	29,928

Net deferred tax asset

The Company's net deferred tax asset (liability) consists of the following:

	December 31,
(in thousands)	2016			2015
Federal losses carryforward	$	4,130		$	5,394
State losses carryforward		13,682			12,751
Research and development carryforward		3,647			3,545
Scientific research and experimental development credit carryforward		16,594			25,771
Intangible assets		-			5,792
Stock compensation		8,389			9,391
Foreign deferrals		58,647			80,920
Inventory reserves		2,273			3,754
Other		5,569			8,484
Deferred tax asset		112,931			155,802
Fixed assets		(30,728	)		(31,925	)
Intangible assets		(5,882	)		(4,760	)
Other		(16,047	)		(17,192	)
Deferred tax liability		(52,657	)		(53,877	)
Valuation allowance		(54,178	)		(90,639	)
Net deferred tax (liabilities)/ asset	$	6,096		$	11,286

Reconciliation of taxes determined by applying U.S. federal statutory rate to loss before provision for income taxes

The provision for income taxes differs from the amount of taxes determined by applying the U.S. federal statutory rate to loss before provision for income taxes as a result of the following:

	Year ended December 31,
(in thousands)	2016			2015			2014
US	$	63,330		$	117,385		$	76,909
International		35,891			18,331			7,285
Earnings before taxes on income		99,221			135,716			84,194

Federal tax at statutory rates	$	34,738		$	47,475		$	29,468
State taxes, net of federal benefit		529			852			650
Impact of foreign operations		(9,937	)		(1,640	)		(1,176	)
Change in valuation allowance		10,458			(950	)		1,091
Effect of foreign rates		(720	)		-			-
Tax credits		(1,572	)		(2,088	)		(1,743	)
Other differences		1,823			733			126
Permanent differences		1,378			(82	)		1,512
Provision for income taxes	$	36,697		$	44,300		$	29,928

Gross unrecognized tax benefits activity

The table below presents the gross unrecognized tax benefits activity for 2016, 2015 and 2014:

(in thousands)
Gross unrecognized tax benefits at December 31, 2013	$	1,121
Increases for tax positions for prior years		150
Decreases for tax positions for prior years		-
Increases for tax positions for current year		102
Settlements		-
Lapse of statute of limitations		(125	)
Gross unrecognized tax benefits at December 31, 2014		1,248
Increases for tax positions for prior years		150
Decreases for tax positions for prior years		-
Increases for tax positions for current year		59
Settlements		-
Lapse of statute of limitations		-
Gross unrecognized tax benefits at December 31, 2015		1,457
Increases for tax positions for prior years		5
Decreases for tax positions for prior years		-
Increases for tax positions for current year		299
Settlements		-
Lapse of statute of limitations		-
Gross unrecognized tax benefits at December 31, 2016	$	1,761

Earnings per share (Tables)

12 Months Ended

Dec. 31, 2016

Earnings per share [Abstract]

Summary of basic and diluted net income per share

The following table presents the calculation of basic and diluted net income per share:

	Years ended December 31,
(in thousands, except share and per share data)	2016			2015			2014
Numerator:
Net income from continuing operations	$	62,524		$	91,416		$	54,266
Interest expense, net of tax		3,255			3,019			2,879
Amortization of debt issuance costs, net of tax		781			868			735
Net income, adjusted from continuing operations		66,560			95,303			57,880
Net loss from discontinued operations		(10,748	)		(28,546	)		(17,525	)
Net income, adjusted	$	55,812		$	66,757		$	40,355

Denominator:
Weighted-average number of shares-basic		40,184,159			38,595,435			37,344,891
Dilutive securities-equity awards		1,054,453			939,882			737,391
Dilutive securities-convertible debt		8,096,500			7,720,525			7,720,525
Weighted-average number of shares-diluted		49,335,112			47,255,842			45,802,807

Net income per share-basic from continuing operations	$	1.56		$	2.37		$	1.45
Net loss per share-basic from discontinued operations		(0.27	)		(0.74	)		(0.47	)
Net income per share-basic	$	1.29		$	1.63		$	0.98

Net income per share-diluted from continuing operations	$	1.35		$	2.02		$	1.26
Net loss per share-diluted from discontinued operations		(0.22	)		(0.61	)		(0.38	)
Net income per share-diluted	$	1.13		$	1.41		$	0.88

Restructuring (Tables)

12 Months Ended

Dec. 31, 2016

Restructuring [Abstract]

Costs of the restructuring

The Company has completed this restructuring. The costs of the restructuring as of December 31, 2016 are detailed below:

	Incurred in		Inception to Date		Total Expected
(in thousands)	2016		Costs Incurred		to be Incurred
Termination benefits	$	5,246	$	5,246	$	5,287
Abandonment of equipment		3,749		3,749		3,749
Other costs		691		691		691
Total	$	9,686	$	9,686	$	9,727

Summary of the activity for liabilities related to EPDU restructuring

The following is a summary of the activity for the liabilities related to the EBOL restructuring:

	Termination
(in thousands)	Benefits
Balance at December 31, 2015	$	-
Expenses incurred		5,246
Amount paid		(889	)
Other adjustments		-
Balance at December 31, 2016	$	4,357

Quarterly financial data (unaudited) (Tables)

12 Months Ended

Dec. 31, 2016

Quarterly financial data (unaudited) [Abstract]

Quarterly financial information

Quarterly financial information for the years ended December 31, 2016 and 2015 is presented in the following tables:

	Quarter Ended
(in thousands, except per share data)	March 31,			June 30,			September 30,			December 31,
2016:
Revenue	$	102,964		$	91,241		$	142,914		$	151,663
Income (loss) from operations		21,157			(2,042	)		35,478			50,929
Net income (loss) from continuing operations		11,889			(2,042	)		20,388			32,289
Net income (loss) from discontinued operations (1)		(7,898	)		(8,905	)		952			5,103
Net income (loss)		3,991			(10,947	)		21,340			37,392

Net income (loss) per share from continuing operations-basic	$	0.30		$	(0.05	)	$	0.50		$	0.80
Net income (loss) per share from discontinued operations-basic		(0.20	)		(0.22	)		0.02			0.13
Net income (loss) per share-basic	$	0.10		$	(0.27	)	$	0.52		$	0.93

Net income (loss) per share from continuing operations-diluted	$	0.26		$	(0.05	)	$	0.43		$	0.67
Net income (loss) per share from discontinued operations-diluted		(0.16	)		(0.22	)		0.02			0.10
Net income (loss) per share-diluted	$	0.10		$	(0.27	)	$	0.45		$	0.77

2015
Revenue	$	52,147		$	119,022		$	158,378		$	159,784
Income (loss) from operations		(21,895	)		35,104			63,159			65,146
Net income (loss) from continuing operations		(15,728	)		22,565			42,088			42,491
Net loss from discontinued operations		(5,792	)		(8,465	)		(5,145	)		(9,144	)
Net income (loss)		(21,520	)		14,100			36,943			33,347

Net income (loss) per share from continuing operations-basic	$	(0.42	)	$	0.59		$	1.08		$	1.08
Net loss per share from discontinued operations-basic		(0.15	)		(0.22	)		(0.14	)		(0.23	)
Net income (loss) per share-basic	$	(0.57	)	$	0.37		$	0.94		$	0.85

Net income (loss) per share from continuing operations-diluted	$	(0.42	)	$	0.50		$	0.90		$	0.90
Net loss per share from discontinued operations-diluted		(0.15	)		(0.18	)		(0.11	)		(0.19	)
Net income (loss) per share-diluted	$	(0.57	)	$	0.32		$	0.79		$	0.71

Summary of significant accounting policies (Details) $ in Thousands		12 Months Ended
	May 19, 2016 shares	Dec. 31, 2016 USD ($) Plan shares	Dec. 31, 2015 USD ($)	Dec. 31, 2014 USD ($)
Accounts, Notes, Loans and Financing Receivable [Line Items]
Unbilled accounts receivable		$ 138,478	$ 113,906
Capitalized interest [Abstract]
Interest costs incurred		8,300	7,800	$ 7,500
Interest costs capitalized		$ 2,200	$ 2,900	$ 2,500
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]
Increase in number of shares of common stock available for issuance (in shares) \| shares	3,800,000
Buildings [Member] \| Minimum [Member]
Property, Plant and Equipment [Line Items]
Estimated useful lives		31 years
Buildings [Member] \| Maximum [Member]
Property, Plant and Equipment [Line Items]
Estimated useful lives		39 years
Building Improvements [Member] \| Minimum [Member]
Property, Plant and Equipment [Line Items]
Estimated useful lives		10 years
Building Improvements [Member] \| Maximum [Member]
Property, Plant and Equipment [Line Items]
Estimated useful lives		39 years
Furniture and Equipment [Member] \| Minimum [Member]
Property, Plant and Equipment [Line Items]
Estimated useful lives		3 years
Furniture and Equipment [Member] \| Maximum [Member]
Property, Plant and Equipment [Line Items]
Estimated useful lives		15 years
Software [Member]
Property, Plant and Equipment [Line Items]
Estimated useful lives		3-7 years or product life
Leasehold Improvements [Member]
Property, Plant and Equipment [Line Items]
Estimated useful lives		Lesser of the asset life or lease term
2006 Plan [Member] \| Stock Options [Member]
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]
Common stock authorized for issuance under the plan (in shares) \| shares		18,900,000
Common stock available for future awards (in shares) \| shares		6,100,000
Contractual life of awards		10 years
Exercise period of options, maximum		10 years
Assumptions used in valuing the stock options granted [Abstract]
Expected dividend yield		0.00%	0.00%	0.00%
Expected average life of options		4 years 3 months 18 days	4 years 3 months 18 days	4 years 6 months
2006 Plan [Member] \| Stock Options [Member] \| Minimum [Member]
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]
Exercise price of option as percentage of fair market value at grant date, minimum		100.00%
Assumptions used in valuing the stock options granted [Abstract]
Expected volatility		31.00%	34.00%	35.00%
Risk-free interest rate		0.93%	1.27%	1.14%
2006 Plan [Member] \| Stock Options [Member] \| Maximum [Member]
Assumptions used in valuing the stock options granted [Abstract]
Expected volatility		33.00%	35.00%	38.00%
Risk-free interest rate		1.22%	1.61%	1.65%
Emergent Plans [Member]
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]
Number of stock based employee compensation plans \| Plan		2
Revenues [Member] \| U.S. Government [Member]
Concentration Risk [Line Items]
Concentration risk percentage		83.00%	86.00%	83.00%
Accounts Receivable [Member] \| U.S. Government [Member]
Concentration Risk [Line Items]
Concentration risk percentage		83.00%	83.00%
Unbilled [Member]
Accounts, Notes, Loans and Financing Receivable [Line Items]
Unbilled accounts receivable		$ 48,039	$ 18,171

Discontinued operations (Details) - USD ($)		12 Months Ended
Discontinued operations (Details) - USD ($)	Aug. 01, 2016	Dec. 31, 2016	Dec. 31, 2015	Dec. 31, 2014
Income Statement, Balance Sheet and Additional Disclosures by Disposal Groups, Including Discontinued Operations [Line Items]
Percentage of outstanding shares distributed	100.00%
Record date for distribution	Jul. 22, 2016
Number of shares received (in shares)	1
Number of shares held (in shares)	2
Number of common stock distributed (in shares)	20,230,000
Term of manufacturing services contract		10 years
Term of transition services agreement		2 years
Assets [Abstract]
Current assets of discontinued operations		$ 0	$ 29,282,000
Non-current assets of discontinued operations		0	76,365,000
Liabilities [Abstract]
Current liabilities of discontinued operations		0	17,348,000
Non-current liabilities of discontinued operations		0	3,234,000
Aptevo [Member]
Income Statement, Balance Sheet and Additional Disclosures by Disposal Groups, Including Discontinued Operations [Line Items]
Unsecured debt	$ 20,000,000
TSA revenue from Aptevo		1,127,778
Manufacturing services revenue		832,108
Revenues [Abstract]
Product sales		21,183,000	27,947,000	$ 30,036,000
Contracts, grants and collaborations		187,000	5,511,000	15,636,000
Total revenues		21,370,000	33,458,000	45,672,000
Operating expense [Abstract]
Cost of product sales		11,556,000	16,809,000	16,449,000
Research and development		18,024,000	34,811,000	46,108,000
Selling, general and administrative		23,792,000	27,313,000	14,248,000
Income (loss) from operations		(32,002,000)	(45,475,000)	(31,133,000)
Other income (expense), net [Abstract]
Other income (expense), net		(41,000)	(472,000)	0
Income (loss) from discontinued operations before provision for (benefit from) income taxes		(32,043,000)	(45,947,000)	(31,133,000)
Provision for (benefit from) income taxes		(21,295,000)	(17,401,000)	(13,608,000)
Net Income (loss) from discontinued operations		(10,748,000)	(28,546,000)	(17,525,000)
Net Cash Provided by (Used in) Discontinued Operations [Abstract]
Net cash (used in) provided by operating activities		(10,299,000)	(12,716,000)	(14,683,000)
Net cash provided by investing activities		(1,926,000)	(1,518,000)	(48,822,000)
Net cash provided by (used in) financing activities		7,733,000	15,012,000	67,219,000
Net increase in cash and cash equivalents		$ (4,492,000)	778,000	$ 3,714,000
Aptevo [Member] \| Disposed of by Sale [Member]
Assets [Abstract]
Cash and cash equivalents	45,000,000
Accounts receivable, net	4,465,000
Inventories	11,959,000
Notes receivable	20,000,000
Other current assets	4,870,000
Current assets of discontinued operations	86,294,000
Property, plant and equipment, net	6,128,000
In-process research and development	41,800,000
Intangible assets, net	15,402,000
Goodwill	13,902,000
Non-current assets of discontinued operations	77,232,000
Total assets of discontinued operations	163,526,000
Liabilities [Abstract]
Accounts payable	6,285,000
Accrued expenses and other current liabilities	64,000
Accrued compensation	2,456,000
Contingent consideration, current portion	191,000
Provision for chargebacks	2,341,000
Deferred revenue, current portion	433,000
Current liabilities of discontinued operations	11,770,000
Deferred revenue, net of current portion	3,232,000
Other liabilities	91,000
Non-current liabilities of discontinued operations	3,323,000
Total liabilities of discontinued operations	$ 15,093,000
Aptevo [Member] \| Held-for-sale [Member]
Assets [Abstract]
Cash and cash equivalents			4,492,000
Accounts receivable, net			6,861,000
Inventories			16,049,000
Prepaid expenses and other current assets			1,880,000
Current assets of discontinued operations			29,282,000
Property, plant and equipment, net			4,046,000
In-process research and development			41,800,000
Intangible assets, net			16,617,000
Goodwill			13,902,000
Non-current assets of discontinued operations			76,365,000
Total assets of discontinued operations			105,647,000
Liabilities [Abstract]
Accounts payable			8,134,000
Accrued expenses and other current liabilities			22,000
Accrued compensation			2,684,000
Contingent consideration, current portion			306,000
Provision for chargebacks			2,238,000
Deferred revenue, current portion			3,964,000
Current liabilities of discontinued operations			17,348,000
Deferred revenue, net of current portion			3,163,000
Other liabilities			71,000
Non-current liabilities of discontinued operations			3,234,000
Total liabilities of discontinued operations			$ 20,582,000

Fair value measurements (Details) - USD ($)
$ in Thousands

12 Months Ended

Dec. 31, 2016

Dec. 31, 2015

Liabilities [Abstract]

Payment of contingent obligations

Unobservable Input Reconciliation [Roll Forward]

Balance, beginning of period

$ 25,155

40,037

Expense (income) included in earnings

(10,857)

(10,884)

Settlements

(1,113)

(4,803)

Purchases, sales and issuances

805

Transfers in/(out) of Level 3

Balance, end of period

13,185

25,155

RSDL [Member]

Liabilities [Abstract]

Fair value adjustment for contingent obligations

(5,400)

(1,500)

Evolva Holding SA 035 & Unither [Member]

Liabilities [Abstract]

Fair value adjustment for contingent obligations

(5,400)

(9,400)

Unobservable Input Reconciliation [Roll Forward]

Contingent value rights based on the novation of the contract

4,000

Fair Value, Measurements, Recurring [Member]

Assets [Abstract]

Investment in money market funds

^[1]

3,323

Total assets

3,323

Liabilities [Abstract]

Contingent price consideration

13,185

25,155

Total liabilities

13,185

25,155

Fair Value, Measurements, Recurring [Member] | Fair Value, Inputs, Level 1 [Member]

Assets [Abstract]

Investment in money market funds

^[1]

3,323

Total assets

3,323

Liabilities [Abstract]

Contingent price consideration

Total liabilities

Fair Value, Measurements, Recurring [Member] | Fair Value, Inputs, Level 2 [Member]

Assets [Abstract]

Investment in money market funds

^[1]

Total assets

Liabilities [Abstract]

Contingent price consideration

Total liabilities

Fair Value, Measurements, Recurring [Member] | Fair Value, Inputs, Level 3 [Member]

Assets [Abstract]

Investment in money market funds

^[1]

Total assets

Liabilities [Abstract]

Contingent price consideration

13,185

25,155

Total liabilities

$ 13,185

$ 25,155

[1]	Included in cash and cash equivalents in accompanying consolidated balance sheets.

Accounts receivable (Details) - USD ($) $ in Thousands	12 Months Ended
Accounts receivable (Details) - USD ($) $ in Thousands	Dec. 31, 2016	Dec. 31, 2015
Accounts, Notes, Loans and Financing Receivable [Line Items]
Accounts receivable, net	$ 138,478	$ 113,906
Increase in unbilled accounts receivable	29,900
Billed [Member]
Accounts, Notes, Loans and Financing Receivable [Line Items]
Accounts receivable, net	90,439	95,735
Unbilled [Member]
Accounts, Notes, Loans and Financing Receivable [Line Items]
Accounts receivable, net	48,039	18,171
Accounts Receivable [Member]
Accounts, Notes, Loans and Financing Receivable [Line Items]
Accounts receivable, net	$ 138,478	$ 113,906

Inventories (Details) - USD ($) $ in Thousands	Dec. 31, 2016	Dec. 31, 2015
Inventories [Abstract]
Raw materials and supplies	$ 30,687	$ 21,275
Work-in-process	19,821	32,709
Finished goods	23,494	6,903
Total inventories	$ 74,002	$ 60,887

Property, plant and equipment (Details) - USD ($) $ in Thousands	12 Months Ended
	Dec. 31, 2016	Dec. 31, 2015	Dec. 31, 2014
Property, Plant and Equipment [Line Items]
Property, plant and equipment	$ 488,004	$ 421,575
Less: Accumulated depreciation and amortization	(111,556)	(93,767)
Total Property, plant and equipment, net	376,448	327,808
Depreciation and amortization	28,023	23,737	$ 22,340
Land and Improvements [Member]
Property, Plant and Equipment [Line Items]
Property, plant and equipment	20,340	16,520
Buildings, Building Improvements and Leasehold Improvements [Member]
Property, Plant and Equipment [Line Items]
Property, plant and equipment	147,130	108,908
Furniture and Equipment [Member]
Property, Plant and Equipment [Line Items]
Property, plant and equipment	190,157	129,933
Software [Member]
Property, Plant and Equipment [Line Items]
Property, plant and equipment	52,564	39,683
Construction-in-progress [Member]
Property, Plant and Equipment [Line Items]
Property, plant and equipment	$ 77,813	$ 126,531

Intangible assets, in-process research and development and goodwill (Details) - USD ($) $ in Thousands	1 Months Ended	12 Months Ended
	Sep. 30, 2015	Dec. 31, 2016	Dec. 31, 2015	Dec. 31, 2014
Intangible Assets [Abstract]
Impairment of Intangible Assets, Indefinite-lived (Excluding Goodwill)		$ 701	$ 9,827	$ 0
Finite-Lived Intangible Assets, Net		33,865		33,865
Goodwill		41,001	41,001
Cost Basis [Abstract]
Intangible Assets, Beginning Balance		57,099
Additions		0
Intangible Assets, Ending Balance		57,099	57,099
Accumulated Amortization [Abstract]
Accumulated Amortization, Beginning Balance		(16,341)
Amortization		6,893	7,376	6,991
Accumulated Amortization, Ending balance		$ (23,234)	(16,341)
Intangible assets, weighted average useful life		75 months
Net book value of intangible assets		$ 33,865		33,865
Finite-Lived Intangible Assets, Amortization Expense, Maturity Schedule [Abstract]
2017		6,217
2018		6,217
2019		5,738
2020		5,657
2021 and beyond		10,036
Finite-Lived Intangible Assets, Net		33,865		$ 33,865
Goodwill, Cost Basis [Abstract]
Goodwill, Beginning Balance		41,001
Goodwill, Additions		0
Goodwill, Ending Balance		41,001	41,001
In-process research and development assets		0	701
EV-035 [Member]
Intangible Assets [Abstract]
Impairment of Intangible Assets, Indefinite-lived (Excluding Goodwill)	$ 9,800
Finite-Lived Intangible Assets, Net	700
Accumulated Amortization [Abstract]
Net book value of intangible assets	700
Finite-Lived Intangible Assets, Amortization Expense, Maturity Schedule [Abstract]
Finite-Lived Intangible Assets, Net	700
Therapeutics and Vaccines [Member]
Goodwill, Cost Basis [Abstract]
Goodwill, Beginning Balance		24,349
Goodwill, Additions		0
Goodwill, Ending Balance		24,349	24,349
Therapeutics and Vaccines [Member] \| EV-035 [Member]
Intangible Assets [Abstract]
Goodwill	$ 22,000
Contract Manufacturing [Member]
Goodwill, Cost Basis [Abstract]
Goodwill, Beginning Balance		6,736
Goodwill, Additions		0
Goodwill, Ending Balance		6,736	6,736
Medical Devices [Member]
Goodwill, Cost Basis [Abstract]
Goodwill, Beginning Balance		9,916
Goodwill, Additions		0
Goodwill, Ending Balance		$ 9,916	$ 9,916

Long-term debt (Details) $ / shares in Units, $ in Thousands			1 Months Ended	9 Months Ended	12 Months Ended
	Aug. 12, 2016 shares $ / shares	Dec. 11, 2013 USD ($) Unit	Jan. 29, 2014 USD ($) shares $ / shares	Sep. 30, 2014	Dec. 31, 2016 USD ($)	Dec. 31, 2015 USD ($)	Dec. 31, 2014 USD ($)
Long-Term Debt [Line Items]
Proceeds from borrowings on long-term indebtedness					$ 0	$ 2,000	$ 1,000
Payments on borrowings on long-term indebtedness					$ 0	0	$ 62,000
BAML Revolving Credit Facility [Memeber]
Long-Term Debt [Line Items]
Maturity date		Dec. 11, 2018
Maximum borrowing capacity		$ 100,000
Credit Agreement [Member]
Long-Term Debt [Line Items]
Number of lending institutions \| Unit		3
Debt covenant, consolidated debt service coverage ratio, minimum					2.50
Debt covenant, leverage ratio, maximum				4.00	3.50		3.75
Debt covenant, minimum cash and liquid investments balance					$ 50,000
2.875% Convertible Senior Notes Due 2021 [Member]
Long-Term Debt [Line Items]
Face amount of debt instrument			$ 250,000
Interest rate percentage			2.875%
Maturity date			Jan. 15, 2021
Conversion rate of notes per $1,000 principal amount (in shares) \| shares	32.3860		30.8821
Conversion price per share (in dollars per share) \| $ / shares	$ 30.88		$ 32.38
Debt issuance costs			$ 8,300
BAML Term Loan [Member]
Long-Term Debt [Line Items]
Debt issuance costs							$ 1,800
Amount of debt issuance costs in other assets, netted against long term debt [Member]
Long-Term Debt [Line Items]
Debt issuance costs						4,900
Amount of debt issuance costs in prepaid and other current assets, netted against long term debt [Member]
Long-Term Debt [Line Items]
Debt issuance costs						$ 1,200

Stockholders' equity (Details) - $ / shares	12 Months Ended
Stockholders' equity (Details) - $ / shares	Dec. 31, 2016	Dec. 31, 2015
Preferred stock
Preferred stock, shares authorized (in shares)	15,000,000	15,000,000
Preferred stock, par value (in dollars per share)	$ 0.001	$ 0.001
Common stock
Common stock, par value (in dollars per share)	$ 0.001	$ 0.001
Common stock, shares authorized (in shares)	200,000,000	100,000,000
Common stock, voting rights	1
Senior Managment [Member]
Treasury Stock [Abstract]
Stock repurchased as part of stock swap (in shares)

Stockholders' equity, share-based compensation arrangements by share-based payment award (Details) - USD ($)		12 Months Ended
	May 19, 2016	Dec. 31, 2016	Dec. 31, 2015	Dec. 31, 2014	Dec. 31, 2013	Jul. 14, 2016
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]
Stock-based compensation expense		$ 18,477,000	$ 15,848,000	$ 12,829,000
Aggregate intrinsic value [Abstract]
Employee Service Share-based Compensation, Nonvested Awards, Compensation Cost Not yet Recognized, Period for Recognition		1 year 10 months 10 days
Employee Service Share-based Compensation, Nonvested Awards, Compensation Not yet Recognized, Stock Options		$ 18,000,000
Share-based Compensation Arrangement by Share-based Payment Award, Number of Additional Shares Authorized	3,800,000
Stock Repurchase Program, Authorized Amount						$ 50,000,000
Employee Service Share-based Compensation, Allocation of Recognized Period Costs [Line Items]
Total stock-based compensation expense		18,477,000	15,848,000	12,829,000
Continuing Operations [Member]
Employee Service Share-based Compensation, Allocation of Recognized Period Costs [Line Items]
Total stock-based compensation expense		17,356,000	14,741,000	11,754,000
Discontinued Operations [Member]
Employee Service Share-based Compensation, Allocation of Recognized Period Costs [Line Items]
Total stock-based compensation expense		1,121,000	1,107,000	1,075,000
Stock Options [Member]
Aggregate Intrinsic Value [Abstract]
Outstanding, beginning of period		52,119,607
Outstanding, end of period		25,348,245	$ 52,119,607
Exercisable, end of period		19,938,451
Options expected to vest, end of period		$ 4,565,548
Aggregate intrinsic value [Abstract]
Weighted average remaining contractual term of options outstanding		4 years	4 years 4 months 24 days
Weighted average remaining contractual term of options exercisable		3 years 2 months 12 days	3 years 4 months 24 days
Weighted average grant date fair value of options granted (in dollars per share)		$ 9.24	$ 8.66		$ 8.84
Total intrinsic value of options exercised		$ 15,600,000	$ 20,200,000	7,500,000
Total fair value of awards vested		$ 16,900,000	$ 14,400,000	12,300,000
2006 Plan [Member] \| Stock Options [Member]
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]
Common stock authorized for issuance under the plan (in shares)		18,900,000
Options outstanding [Roll Forward]
Outstanding, beginning of period (in shares)		2,964,237
Granted (in shares)		411,698
Exercised (in shares)		(809,638)
Forfeited (in shares)		(96,293)
Cancelled (in shares)		(146,986)
Equitable adjustment (in shares)		236,313
Outstanding, end of period (in shares)		2,559,331	2,964,237
Exercisable, end of period (in shares)		1,504,855
Options expected to vest, end of period (in shares)		849,184
Weighted-Average Exercise Price [Roll Forward]
Outstanding, beginning of period (in dollars per share)		$ 22.73
Granted (in dollars per share)		33.61
Exercised (in dollars per share)		19.41
Forfeited (in dollars per share)		26.67
Cancelled (in dollars per share)		28.33
Equitable adjustment (in dollars per share)		22.90
Outstanding, end of period (in dollars per share)		22.94	$ 22.73
Exercisable, end of period (in dollars per share)		19.59
Options expected to vest, end of period (in dollars per share)		$ 27.46
2006 Plan [Member] \| Restricted Stock Units (RSUs) [Member]
Restricted stock unit award activity [Roll Forward]
Outstanding, beginning of period (in shares)		889,004
Granted (in shares)		515,782
Vested (in shares)		(420,599)
Forfeited (in shares)		(80,428)
Cancelled (in shares)		(107,514)
Equitable adjustment (in shares)		79,339
Outstanding, end of period (in shares)		875,584	889,004
Weighted-Average Grant Price [Roll Forward]
Outstanding, beginning of period (in dollars per share)		$ 26.86
Granted (in dollars per share)		34.00
Vested (in dollars per share)		24.68
Forfeited (in dollars per share)		29.40
Cancelled (in dollars per share)		30.90
Equitable adjustment (in dollars per share)		28.86
Outstanding, end of period (in dollars per share)		$ 28.94	$ 26.86
Aggregate intrinsic value [Abstract]
Outstanding, beginning of period		$ 35,569,048
Outstanding, end of period		$ 28,754,179	$ 35,569,048
2004 Plan [Member] \| Stock Options [Member]
Options outstanding [Roll Forward]
Outstanding, beginning of period (in shares)		29,699
Granted (in shares)		0
Exercised (in shares)		(29,699)
Forfeited (in shares)		0
Outstanding, end of period (in shares)		0	29,699
Exercisable, end of period (in shares)		0
Options expected to vest, end of period (in shares)		0
Weighted-Average Exercise Price [Roll Forward]
Outstanding, beginning of period (in dollars per share)		$ 10.28
Granted (in dollars per share)		0
Exercised (in dollars per share)		10.28
Forfeited (in dollars per share)		0
Outstanding, end of period (in dollars per share)		0	$ 10.28
Exercisable, end of period (in dollars per share)		0
Options expected to vest, end of period (in dollars per share)		$ 0
Cost of Product Sales [Member] \| Continuing Operations [Member]
Employee Service Share-based Compensation, Allocation of Recognized Period Costs [Line Items]
Total stock-based compensation expense		$ 997,000	$ 1,183,000	1,145,000
Research and Development [Member] \| Continuing Operations [Member]
Employee Service Share-based Compensation, Allocation of Recognized Period Costs [Line Items]
Total stock-based compensation expense		2,297,000	2,324,000	2,779,000
Selling, General and Administrative [Member] \| Continuing Operations [Member]
Employee Service Share-based Compensation, Allocation of Recognized Period Costs [Line Items]
Total stock-based compensation expense		$ 14,062,000	$ 11,234,000	$ 7,830,000

Income taxes (Details) - USD ($) $ in Thousands	12 Months Ended
Income taxes (Details) - USD ($) $ in Thousands	Dec. 31, 2016	Dec. 31, 2015	Dec. 31, 2014
Current
Federal	$ 29,244	$ 38,957	$ 22,988
State	2,331	2,221	959
International	1,002	2,029	828
Total current	32,577	43,207	24,775
Deferred
Federal	9,979	(119)	3,332
State	(272)	(111)	209
International	(5,587)	1,323	1,612
Total deferred	4,120	1,093	5,153
Total provision for income taxes	36,697	44,300	29,928
Net deferred tax asset [Abstract]
Net operating loss carryforward (federal)	4,130	5,394
Net Operating Loss Carryforward (state)	13,682	12,751
Research and development carryforward	3,647	3,545
Scientific research and experimental development credit carryforward	16,594	25,771
Intangible assets	0	5,792
Stock compensation	8,389	9,391
Foreign deferrals	58,647	80,920
Inventory reserves	2,273	3,754
Other	5,569	8,484
Deferred tax asset	112,931	155,802
Fixed assets	(30,728)	(31,925)
Intangible assets	(5,882)	(4,760)
Other	(16,047)	(17,192)
Deferred tax liability	(52,657)	(53,877)
Valuation allowance	(54,178)	(90,639)
Net deferred tax asset	6,096	11,286
Operating Loss Carryforwards [Line Items]
Deferred Tax Assets, Valuation Allowance	54,178	90,639
Income tax reconciliation [Abstract]
US	63,330	117,385	76,909
International	35,891	18,331	7,285
Earnings before taxes on income	99,221	135,716	84,194
Federal tax at statutory rates	34,738	47,475	29,468
State taxes, net of federal benefit	529	852	650
Impact of foreign operations	(9,937)	(1,640)	(1,176)
Change in valuation allowance	10,458	(950)	1,091
Effect of foreign rates	(720)
Tax credits	(1,572)	(2,088)	(1,743)
Other differences	1,823	733	126
Permanent differences	1,378	(82)	1,512
Total provision for income taxes	$ 36,697	$ 44,300	$ 29,928
Effective annual tax rate	37.00%	33.00%	36.00%
Research and Development Tax Credit [Member]
Tax Credit Carryforward [Line Items]
Tax credit carryforward, amount	$ 3,700
Tax credit carryforwards, expiration date	Dec. 31, 2023
Canadian Federal Scientific Research And Experimental Development [Member]
Tax Credit Carryforward [Line Items]
Tax credit carryforward, amount	$ 500
Tax credit carryforwards, expiration date	Dec. 31, 2027
Manitoba Scientific Research And Experimental Development [Member]
Tax Credit Carryforward [Line Items]
Tax credit carryforward, amount	$ 16,100
Tax credit carryforwards, expiration date	Dec. 31, 2024
U.S. Federal Tax Authority [Member]
Operating Loss Carryforwards [Line Items]
Net operating loss carryforwards	$ 11,800
Operating loss carryforwards, expiration year	Dec. 31, 2026
State and Local Jurisdiction [Member]
Net deferred tax asset [Abstract]
Valuation allowance	$ (191,700)
Operating Loss Carryforwards [Line Items]
Net operating loss carryforwards	$ 255,100
Operating loss carryforwards, expiration year	Dec. 31, 2018
Deferred Tax Assets, Valuation Allowance	$ 191,700
Foreign Tax Authority [Member]
Operating Loss Carryforwards [Line Items]
Net operating loss carryforwards	$ 170,300
Period of change in the nature or conduct of business following change in ownership	3 years
U.S. Federal Tax Authority - Tax Effected [Member]
Operating Loss Carryforwards [Line Items]
Net operating loss carryforwards	$ 4,100
State and Local Jurisdiction - Tax Effected [Member]
Net deferred tax asset [Abstract]
Valuation allowance	(10,300)
Operating Loss Carryforwards [Line Items]
Net operating loss carryforwards	13,700
Deferred Tax Assets, Valuation Allowance	10,300
Canadian Federal Gross [Member]
Net deferred tax asset [Abstract]
Valuation allowance	(43,600)
Operating Loss Carryforwards [Line Items]
Deferred Tax Assets, Valuation Allowance	43,600
Canadian Federal Tax Effected [Member]
Net deferred tax asset [Abstract]
Valuation allowance	(11,700)
Operating Loss Carryforwards [Line Items]
Deferred Tax Assets, Valuation Allowance	11,700
Foreign Tax Authority Tax Effected [Member]
Net deferred tax asset [Abstract]
Valuation allowance	(43,900)
Operating Loss Carryforwards [Line Items]
Deferred Tax Assets, Valuation Allowance	$ 43,900

Income taxes, income tax contingency (Details) - USD ($)	12 Months Ended
	Dec. 31, 2016	Dec. 31, 2015	Dec. 31, 2014
Income Tax Contingency [Line Items]
Unrecognized tax benefits, current	$ 500,000	$ 318,000
Unrecognized tax benefits, noncurrent	1,300,000	1,064,000
Gross unrecognized tax benefits activity [Roll Forward]
Gross unrecognized tax benefits, beginning balance	1,457,000	1,248,000	$ 1,121,000
Increases for tax positions for prior years	5,000	150,000	150,000
Decreases for tax positions for prior years	0	0	0
Increases for tax positions for current year	299,000	59,000	102,000
Settlements	0	0	0
Lapse of statute of limitations	0	0	(125,000)
Gross unrecognized tax benefits, ending balance	$ 1,761,000	$ 1,457,000	$ 1,248,000
U.S. Federal Tax Authority [Member] \| Minimum [Member]
Gross unrecognized tax benefits activity [Roll Forward]
Open tax year	2011
Federal income tax year selected for audit	2011
U.S. Federal Tax Authority [Member] \| Maximum [Member]
Gross unrecognized tax benefits activity [Roll Forward]
Open tax year	2015
Federal income tax year selected for audit	2012
United Kingdom Tax Authority [Member] \| Minimum [Member]
Gross unrecognized tax benefits activity [Roll Forward]
Open tax year	2007
United Kingdom Tax Authority [Member] \| Maximum [Member]
Gross unrecognized tax benefits activity [Roll Forward]
Open tax year	2015

Purchase commitment (Details) - USD ($)	12 Months Ended
Purchase commitment (Details) - USD ($)	Dec. 31, 2016	Dec. 31, 2015	Dec. 31, 2014
Purchase commitment [Abstract]
Total purchase commitment to Norwood Laboratories Inc.		$ 0	$ 15,200,000
Materials purchased from Norwood Laboratories Inc as of December 31, 2014	$ 4,500,000	$ 6,200,000	$ 1,500,000

401(k) savings plan (Details) - USD ($) $ in Millions	12 Months Ended
401(k) savings plan (Details) - USD ($) $ in Millions	Dec. 31, 2016	Dec. 31, 2015	Dec. 31, 2014
401(k) savings plan [Abstract]
Matching of qualified deferrals by employer, maximum	50.00%
Percentage of employee's gross salary subject to employer's matching contribution	6.00%
Matching contributions made by employer	$ 2.5	$ 2.2	$ 2.1

Related party transactions (Details) $ in Millions	12 Months Ended
Related party transactions (Details) $ in Millions	Dec. 31, 2016 USD ($)
Related Party Transaction [Line Items]
Costs incurred from services rendered under marketing/consulting agreement	$ 0.2
Saudi Arabia [Member]
Related Party Transaction [Line Items]
Percentage of net sales of biodefense products subject to payment to related party	17.50%
Qatar [Member]
Related Party Transaction [Line Items]
Percentage of net sales of biodefense products subject to payment to related party	15.00%
United Arab Emirates [Member]
Related Party Transaction [Line Items]
Percentage of net sales of biodefense products subject to payment to related party	15.00%

Earnings per share (Details) - USD ($) $ / shares in Units, $ in Thousands	3 Months Ended								12 Months Ended
	Dec. 31, 2016	Sep. 30, 2016	Jun. 30, 2016	Mar. 31, 2016	Dec. 31, 2015	Sep. 30, 2015	Jun. 30, 2015	Mar. 31, 2015	Dec. 31, 2016	Dec. 31, 2015	Dec. 31, 2014
Numerator [Abstract]
Net Income from continuing operations	$ 32,289	$ 20,388	$ (2,042)	$ 11,889	$ 42,491	$ 42,088	$ 22,565	$ (15,728)	$ 62,524	$ 91,416	$ 54,266
Interest expense, net of tax									3,255	3,019	2,879
Amortization of debt issuance costs, net of tax									781	868	735
Net income, adjusted from continuing operations									66,560	95,303	57,880
Income (loss) from discontinued operations	$ 5,103	$ 952	$ (8,905)	$ (7,898)	$ (9,144)	$ (5,145)	$ (8,465)	$ (5,792)	(10,748)	(28,546)	(17,525)
Net income (loss), adjusted									$ 55,812	$ 66,757	$ 40,355
Denominator [Abstract]
Weighted-average number of shares-basic (in shares)									40,184,159	38,595,435	37,344,891
Dilutive securities-equity awards (in shares)									1,054,453	939,882	737,391
Dilutive securities-convertible debt									8,096,500	7,720,525	7,720,525
Weighted-average number of shares-diluted (in shares)									49,335,112	47,255,842	45,802,807
Net income per share - basic from continuing operations (in dollars per share)	$ 0.80	$ 0.50	$ (0.05)	$ 0.30	$ 1.08	$ 1.08	$ 0.59	$ (0.42)	$ 1.56	$ 2.37	$ 1.45
Net loss from discontinued operations-basic	0.13	0.02	(0.22)	(0.20)	(0.23)	(0.14)	(0.22)	(0.15)	(0.27)	(0.74)	(0.47)
Net income per share - basic (in dollars per share)	0.93	0.52	(0.27)	0.10	0.85	0.94	0.37	(0.57)	1.29	1.63	0.98
Net income per share - diluted from continuing operations (in dollars per share)	0.67	0.43	(0.05)	0.26	0.90	0.90	0.50	(0.42)	1.35	2.02	1.26
Net loss per share from discontinued operations-basic	0.10	0.02	(0.22)	(0.16)	(0.19)	(0.11)	(0.18)	(0.15)	(0.22)	(0.61)	(0.38)
Net income per share-diluted	$ 0.77	$ 0.45	$ (0.27)	$ 0.10	$ 0.71	$ 0.79	$ 0.32	$ (0.57)	$ 1.13	$ 1.41	$ 0.88
Stock Options [Member]
Antidilutive Securities Excluded from Computation of Earnings Per Share [Line Items]
Antidilutive shares excluded from calculation (in shares)											1,400,000

Restructuring (Details) - USD ($) $ in Thousands	12 Months Ended
Restructuring (Details) - USD ($) $ in Thousands	Dec. 31, 2016	Dec. 31, 2015	Dec. 31, 2014
Summary of activity for liabilities [Roll Forward]
Impairment of idled equipment	$ 5,569	$ 1,147	$ 0
Selling, General and Administrative Expenses [Member]
Summary of activity for liabilities [Roll Forward]
Impairment of idled equipment	3,700
EBOL Restructuring Plan [Member]
Restructuring Cost and Reserve [Line Items]
Incurred in 2016	9,686
Inception to Date Costs Incurred	9,686
Total Expected to be Incurred	9,727
Termination Benefits [Member]
Summary of activity for liabilities [Roll Forward]
Balance, beginning of period	0
Expenses incurred	5,246
Amount paid	(889)
Other adjustments	0
Balance, end of period	4,357	$ 0
Termination Benefits [Member] \| EBOL Restructuring Plan [Member]
Restructuring Cost and Reserve [Line Items]
Incurred in 2016	5,246
Inception to Date Costs Incurred	5,246
Total Expected to be Incurred	5,287
Abandonment of Equipment [Member] \| EBOL Restructuring Plan [Member]
Restructuring Cost and Reserve [Line Items]
Incurred in 2016	3,749
Inception to Date Costs Incurred	3,749
Total Expected to be Incurred	3,749
Other Costs [Member] \| EBOL Restructuring Plan [Member]
Restructuring Cost and Reserve [Line Items]
Incurred in 2016	691
Inception to Date Costs Incurred	691
Total Expected to be Incurred	691
Retention Payments [Member]
Summary of activity for liabilities [Roll Forward]
Amount paid	$ 2,000

Segment information (Details) $ in Thousands	12 Months Ended
Segment information (Details) $ in Thousands	Dec. 31, 2016 USD ($) Segment	Dec. 31, 2015 USD ($)	Dec. 31, 2014 USD ($)
Segment Reporting Information [Line Items]
Number of independent public companies \| Segment	2
Number of business segments \| Segment	1
Long-lived assets	$ 970,111	$ 1,037,484
Research and development	108,290	119,186	$ 104,721
Interest revenue	1,053	572	320
Interest expense	(7,617)	(6,523)	(8,240)
Depreciation and amortization	28,023	23,737	22,340
Net income	51,776	62,870	36,741
Intangible assets	33,865	40,758
In-process research and development assets	0	701
Goodwill, net book value	41,001	41,001
Total assets	970,111	1,037,484
Expenditures for long-lived assets	$ 76,257	$ 44,812	$ 30,673
Revenue [Member] \| United States [Member]
Segment Reporting Information [Line Items]
Concentration risk percentage	96.00%	98.00%	96.00%
Revenue [Member] \| U.S. Government [Member]
Segment Reporting Information [Line Items]
Concentration risk percentage	80.00%	89.00%	87.00%
Foreign Jurisdictions [Member]
Segment Reporting Information [Line Items]
Long-lived assets	$ 28,400	$ 25,800
Total assets	$ 28,400	$ 25,800

Quarterly financial data (unaudited) (Details) - USD ($) $ / shares in Units, $ in Thousands	3 Months Ended								12 Months Ended
	Dec. 31, 2016	Sep. 30, 2016	Jun. 30, 2016	Mar. 31, 2016	Dec. 31, 2015	Sep. 30, 2015	Jun. 30, 2015	Mar. 31, 2015	Dec. 31, 2016	Dec. 31, 2015	Dec. 31, 2014
Quarterly financial data (unaudited) [Abstract]
Revenue	$ 151,663	$ 142,914	$ 91,241	$ 102,964	$ 159,784	$ 158,378	$ 119,022	$ 52,147	$ 488,782	$ 489,331	$ 404,466
Income from operations	50,929	35,478	(2,042)	21,157	65,146	63,159	35,104	(21,895)
Net income from continuing operations	32,289	20,388	(2,042)	11,889	42,491	42,088	22,565	(15,728)	62,524	91,416	54,266
Income (loss) from discontinued operations	5,103	952	(8,905)	(7,898)	(9,144)	(5,145)	(8,465)	(5,792)	(10,748)	(28,546)	(17,525)
Net income	$ 37,392	$ 21,340	$ (10,947)	$ 3,991	$ 33,347	$ 36,943	$ 14,100	$ (21,520)	$ 51,776	$ 62,870	$ 36,741
Net income per share from continuing operations-basic (in dollars per share)	$ 0.80	$ 0.50	$ (0.05)	$ 0.30	$ 1.08	$ 1.08	$ 0.59	$ (0.42)	$ 1.56	$ 2.37	$ 1.45
Net loss per share from discontinued operations-basic (in dollars per share)	0.13	0.02	(0.22)	(0.20)	(0.23)	(0.14)	(0.22)	(0.15)	(0.27)	(0.74)	(0.47)
Net income per share - basic (in dollars per share)	0.93	0.52	(0.27)	0.10	0.85	0.94	0.37	(0.57)	1.29	1.63	0.98
Net income per share from continuing operations-diluted (in dollars per share)	0.67	0.43	(0.05)	0.26	0.90	0.90	0.50	(0.42)	1.35	2.02	1.26
Net loss per share from discontinued operations-diluted (in dollars per share)	0.10	0.02	(0.22)	(0.16)	(0.19)	(0.11)	(0.18)	(0.15)	(0.22)	(0.61)	(0.38)
Net income per share-diluted	$ 0.77	$ 0.45	$ (0.27)	$ 0.10	$ 0.71	$ 0.79	$ 0.32	$ (0.57)	$ 1.13	$ 1.41	$ 0.88